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Abstract Background Autism spectrum disorder (ASD) is a complex neurodevelopmental condition with rising global prevalence. Current management strategies predominantly address behavioral symptoms rather than core neurobi...

Abstract Background Acute liver failure (ALF) is a life-threatening syndrome characterized by rapid deterioration of liver function, resulting in high mortality and posing a substantial global health burden. Human embryo...

Abstract Background Recruitment and retention remain persistent challenges in Alzheimer’s disease (AD) clinical trials, particularly as studies increasingly focus on earlier disease stages and require longer participat...

Abstract Background Children with Unilateral Cerebral Palsy (UCP) are characterized by significant upper limbs (ULs) impairment that hinders daily activities and participation, requiring accurate assessment. Although mot...

Abstract Immune checkpoint inhibitors (ICIs) have fundamentally altered the therapeutic paradigm for head and neck squamous cell carcinoma (HNSCC); however, durable clinical benefit remains limited to biologically define...

Abstract Background This is the first systematic review and meta-analysis aimed at assessing the current status of robotic-assisted implant surgery (r-CAIS) in zygomatic implant (ZI) placement, with a particular focus on...

Abstract Background Hereditary angioedema (HAE) is a rare, potentially life-threatening genetic disorder that is caused by C1-inhibitor (C1INH) deficiency or dysfunction. This scoping review sought to map recent advances...

Abstract Background Coronary collateral circulation may limit myocardial injury during ST-elevation myocardial infarction (STEMI), but the magnitude of this association with mortality in contemporary practice remains unc...

Abstract Background Thoracic surgery involves complex diseases and critically ill patients, demanding doctors to integrate solid theoretical knowledge with practical skills. Clinical medical students, however, often stru...

Abstract Background Idiopathic pulmonary fibrosis (IPF) is associated with heavy symptom burden, limited treatment options, poor prognosis, and significant economic burden, and severely impairs health-related quality of ...

Abstract Purpose Structured reporting (SR) offers standardized radiological documentation, enhancing clarity and reproducibility. However, its role in contrast-enhanced ultrasound (CEUS) for testicular tumors remains und...

Abstract Background The triglyceride-glucose (TyG) index has emerged as a surrogate marker for insulin resistance. This systematic review and meta-analysis of observational studies aimed to investigate the association be...