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Abstract Background Digital teaching methods are established for imparting theoretical knowledge in the training of health professions. While digital formats are increasingly used in education, evidence on their capacity...

Abstract Background Environmental studies often evaluate how exposures influence health outcomes through intermediate biological processes. In practice, researchers are often interested in complex exposure mixtures rathe...

Abstract Background As there are no recommendations on handling missing values in a dichotomous index test of a diagnostic study, researchers often ignore missing values in the analysis or use simple methods. Thus, this ...

Abstract Background Leishmaniasis is a vector-borne disease caused by a protozoan parasite of the genus Leishmania. The infection is transmitted by the bite of infected female sandflies of the genus Phlebotomus in the Ol...

Abstract Background Receiver Operating Characteristic (ROC) analysis is commonly used to evaluate how well biomarkers distinguish between diseased and non-diseased individuals. A very important step in this process is ch...

Abstract Background Programmed death-ligand 1 (PD-L1) is widely used as a predictive biomarker for response to immune checkpoint inhibitors in gastric cancer (GC); however, its independent prognostic value for overall su...

Abstract Introduction Quantitative bias analysis (QBA) methods have been developed, with growing applications to epidemiological studies. Bayesian QBA (BQBA) methods may be superior in effectively using evidence-based pr...

Abstract Background Machine learning methods are widely used to detect behavioural data patterns. Although these new mathematical methods are useful tools, the interpretation of the results are often ambivalent unless ...

Abstract A selective and eco-friendly spectrophotometric approach was developed for the quantitative determination of entacapone (ENT) in the presence of its co-formulated drugs carbidopa (CAR) and levodopa (LEV) which e...

Abstract Background The objective of this in vitro study was to assess the anti-biofilm efficacy of super-oxidized water and ozonated water, activated through various methods, against Enterococcus faecalis (E. faecalis) ...