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Abstract Background Maternal and perinatal quality collaboratives (M/PQCs) across nearly all U.S. states focus on improving health care and outcomes for birth parents and their infants. In the context of increases in mat...

Abstract Background Insomnia, which is a common complaint among older adults, is associated with cognitive deterioration and a lower quality of life. Kami Guibi-tang (KGT), traditional Eastern herbal medicine, is known t...

Abstract Background Shift workers are disproportionately exposed to institutional food environments shaped by long working hours and irregular schedules. In rapidly industrializing cities, institutional fast-food availab...

Abstract Background Diabetic Foot Ulcers (DFUs) represent a global healthcare challenge, imposing substantial socioeconomic burdens due to their increasing incidence and associated mortality. This study evaluates the eff...

Abstract Background/objectives Cardiovascular diseases (CVDs), particularly myocardial infarction (MI) and heart failure (HF), remain global causes of morbidity and mortality, despite the current treatment options. Stem ...

Abstract Background Acute liver failure (ALF) is a life-threatening syndrome characterized by rapid deterioration of liver function, resulting in high mortality and posing a substantial global health burden. Human embryo...

Abstract Background Vasomotor symptoms are common during menopause and can impair quality of life. Although hormone therapy is effective, concerns about risks and adverse effects contribute to limited utilization, highli...

Abstract Background AP01, a novel formulation of inhaled pirfenidone, has demonstrated potential for improved efficacy and safety for idiopathic pulmonary fibrosis (IPF) vs. oral pirfenidone. A 72-week phase 1b study, AT...

Abstract Background Neuraxial block failure in obese parturients is a significant clinical challenge, leading to inadequate pain relief and increased maternal risk. Novel techniques such as the Combined Spinal-Epidural (...

Abstract Knee osteoarthritis (KOA) is a degenerative joint condition characterized by progressive cartilage deterioration and chronic pain, leading to functional impairment. Bone marrow-derived orthobiologics, such as bo...

Abstract Background Cerumen impaction is a common, preventable cause of hearing loss that affects up to 30% of the global population. Despite its high burden, management practices vary widely, highlighting the need for c...

Abstract Asthma is a chronic inflammatory airway disease with a rising global prevalence and impact on quality of life. Conventional therapeutics such as corticosteroids and β2-agonists are associated with various long-...

Abstract Background Postherpetic neuralgia (PHN) is a neuropathic pain syndrome that can be resistant to traditional therapies and severely impairs quality of life. The serratus posterior superior intercostal plane block...