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Depression and burnout are linked to a higher risk for the development of cardiovascular diseases. Physical activity has the potential to enhance prognosis of cardiovascular diseases and improve depression and burnout sy...

Objective: This study aimed to investigate the association of body roundness index (BRI) with all-cause and cardiovascular mortality in patients with cardiovascular-kidney-metabolic (CKM) syndrome stages 0–3. Methods: ...

Lipoprotein(a) [Lp(a)] is a useful marker for cardiovascular risk stratification. Previous studies have shown higher Lp(a) levels in women than in men and sex differences in its association with atherosclerosis. The aim ...

Background: Neuropsychiatric disorders are highly prevalent, significantly impacting patients' Quality of Life. Probiotics can modulate the balance of gut flora, ameliorating neuropsychiatric disorders and ultimately red...

Background: Endothelial dysfunction (ED) is a key pathophysiological mechanism in cardiovascular diseases (CVD). The Endothelial Activation and Stress Index (EASIX), derived from routine laboratory markers, has been prop...

Background: Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality in patients with type 2 diabetes mellitus. Understanding diabetes patients' knowledge and perception of CVD risk factors is es...

Introduction and Aims: Evidence suggests a relationship between oral microbiota and cardiovascular diseases (CVDs). However, the roles of specific microbiota in the pathogenesis of CVDs remain underexplored. Methods: Two...

Objective: To examine the associations of phenotypic age acceleration (PAA) with all-cause and cardiovascular mortality among U.S. adults at risk for heart failure. Methods: We analyzed 19,665 participants aged ≥20 ye...

Study objective: Systemic inflammation increases the risk of cardiovascular events and is often present in patients with atherosclerotic cardiovascular disease (ASCVD), particularly in those who also have chronic kidney ...

Oxidative stress (OS), derived from an imbalance between reactive oxygen species (ROS) accumulation and impaired antioxidant defense, is a recognized cause of atherothrombosis, through a complex interaction between low-g...

Globally, one major cause of morbidity and mortality is cardiovascular diseases (CVDs). The burden of cardiovascular disease among the elderly is still high and typically tends to move to nations with lower sociodemograp...

Oropharyngeal infection has long been associated with cardiovascular disease (CVD), specifically valvular disease and endocarditis. However, the relationship between periodontal disease (PD), with associated infection an...

Background: Adults aged 75 years and older carry the highest absolute risk of cardiovascular disease (CVD) yet remain substantially underrepresented in randomized trials evaluating statin therapy for primary prevention. ...

Aims: Clinical trials showed that statin therapy decreased cardiovascular events without significantly raising the level of transaminases. However, the information in subjects with altered liver test at baseline is more ...