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Oxidative stress–induced cellular injury is a key mechanism underlying tissue dysfunction, and food-derived phenolic compounds have attracted interest as natural modulators of redox homeostasis. Sensory cells, includin...

The targeted-modified low-molecular-weight pectin (LMP), a natural polysaccharide derived from citrus fruits, represents a promising food-derived immunomodulatory agent. This study assessed the efficacy of targeted-modif...

Huangjing (Polygonati Rhizoma) is an important medicinal and edible herb, which can be taken orally, brewed in tea, steeped in wine, or used in food processing.The fibrous roots of Polygonum cyrtonema, usually discarded ...

Background: Osteoporosis has long been considered a disorder confined to bone tissue. Growing evidence now highlights its systemic origins, governed by intricate communication between multiple organs. The multi-organ-bon...

Purpose: To explore how blue light-emitting diode (LED) exposure affects ferritinophagy and iron homeostasis in the conjunctival epithelium. Methods: C57BL/6 J mice and human conjunctival epithelial cells were exposed ...

Chlorfenapyr (CHL) is a widely used insecticide whose expanding application raises concerns about cardiotoxicity following both acute poisoning and chronic environmental exposure. The mechanisms underlying its cardiac in...

Introduction and aims: Increasing evidence suggests that marginal zone B and B1 cell-specific protein (MZB1) plays crucial roles in inflammatory responses, endoplasmic reticulum (ER) stress, and cell survival, but its fu...

Microalgae are promising platforms for CO2 mitigation. However, high CO2 exposure can impose physiological and environmental constraints, such as acidification and disruption of cellular homeostasis, which impair sensiti...

Hepatic-driven metabolic alterations have impacts on both embryo implantation and subsequent fetal development. We previously found that dietary chenodeoxycholic acid (CDCA) improves maternal redox homeostasis and metabo...

Neurotransmitters play fundamental regulatory roles within the central nervous system (CNS), where they modulate neuronal signaling and maintain neural network homeostasis. Beyond their classical functions in the CNS, th...