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Vehicles and enhancers effect on in vitro probenecid permeation through dermatomed abdominal pig skin was investigated. The permeability of different probenecid percentages dispersed in vehicles as vaseline, carbopol/e...

The objective of this work was to investigate feasibility of transdermal delivery of loratadine. Effect of pH, vehicles and chemical enhancers on the skin permeation of loratadine was studied in vitro, using rat abdomina...

A self-emulsifying drug delivery system (SEDDS) of a poorly water soluble drug, irbesartan (IRB), was designed. The aim was to improve the solubility as well as dissolution rates of IRB. Solubility of IRB in different ...

Hydroquinone (HQ) is a drug reported to possess manifold biological activities. HQ is highly unstable into various topical vehicles, presenting low topical bioavailability and a relevant level of toxicity. The Pluronic®...

Las microemulsiones son mezclas isotrópicas, estables, claras, constituidas por una fase oleosa, una acuosa y uno o más anfifílicos. Despiertan interés a nivel farmacéutico debido a varias ventajas que ofrecen: ca...