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Acute phosphate nephropathy is a form of acute kidney injury (AKI) due to oral sodium phosphate (ONaP) purgatives used for bowel cleansing before colonoscopy. Usually, 45 ml ONaP is given two times daily 12-24 hours prio...

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the development of antibodies against a variety of nuclear and cytoplasmic antigens. SLE renal involvement is referred to as ‘lupus nephritis...

BACKROUND: The renin-angiotensin-aldosterone system plays a central role in fibrinolysis. Activation of the RAAS stimulates the expression of plasminogen activator inhibitor (PAI-1), which can be directly implicated in t...

Therapy of the anemia is a serious problem in patients with chronic renal failure. Several reports on adult patients have shown that supplementation with Lcarnitine can decrease the requirement for rhEPO. We investigated...

OBJECTIVE: Atherosclerotic vascular disease (AVD) is the most frequent complication seen in hemodialysis (HD) patients. Evidence suggests that inflammation may play a role in the pathogenesis and progression of atheroscl...

Plasma carnitine levels and the effect of oral Lcarnitine supplementation on trigliceride and free faty acid levels were investigated in twenty uremic children on peritoneal dialysis. No difference was found between p...

In this study, the aim is to observe the renin-angiotensin system (RAS) and endothelium after phlebotomy in healthy blood donors. Healthy blood donors were divided into two subgroups according to the presence of hyperten...

Medullary sponge kidney (MSK) is known as a congenital disesase with dilatation of collecting tubules. MSK is usually asymptomatic but various clinical manifestations may occur including nephrocalcinosis, renal tubular a...

OBJECTIVE: Vitamin D insufficiency might have a role in numerous diseases including autoimmune disease, cancer, diabetes mellitus, hypertension and heart diseases. The relationship between vitamin D insufficiency and hyp...

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OBJECTIVE: To evaluate the change in osteoporosis rate and bone mineral density (BMD) in a cohort hyponatremic versus normonatremic patients under 12-month osteoporosis treatment. MATERIAL and METHODS: A total of 280 ...

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Classic polyarteritis nodosa (cPAN) is a systemic necrotizing vasculitis of medium-sized muscular arteries. Glomerular involvement is not expected in the course of cPAN. Herein, we describe a case of cPAN with glomerular...

The amount of protein in the diet is one of the factors determining the rate of progression of chronic renal failure. Since 1980, reducing dietary protein intake has received most attention as a potential intervention to...

OBJECTIVE: Protein-energy wasting (PEW) and inflammation are common and related to increased cardiovascular mortality in hemodialysis (HD) patients. Herein, we aimed to investigate the relationships between adipocytokine...

Nonvalvular atrial fibrillation is the most prevalent sustained arrhythmia in chronic kidney disease patients. When compared to warfarin, new oral anticoagulants are found to be non-inferior or superior in safety and eff...

Linezolid is a drug used frequently for the treatment of infections due to resistant gram-positive bacteria including methicillin-resistant Stapylococcus aereus (MRSA), penicillin-resistant pneumococcus and vancomycin-re...

Measurement of glomerular area and volume have been studied for native kidney biopsies, but much less for renal transplant biopsies. Relationship of histopathological findings of zero hour biopsies with baseline glomerul...

OBJECTIVES: Recently, angiotensin II (Ang II) receptorsubtype I binding sites has been demonstrated on bone cell precursors and extensive area of research has been focused on the effects of renin angiotensin system (RAS)...

Venous access with a central catheter is typically a necessary technique for hemodialysis. Although, central venous catheters are widely used, they may cause life-threatening complications by migration of fractured cathe...

BACKGROUND/AIMS: Despite the increasing evidence for the role of nitric oxide (NO) in hemodialysis hypotension, the source of NO is still debated. Heparin stimulates NO production by the cultured human endothelial cells ...

OBJECTIVE: Dialysate concentrations of CA-125 refl ect the mesothelial cell mass. In patients with peritoneal dialysis ultrafi ltration failure, low concentrations of CA-125 have been demonstrated. Statins have anti-infl...