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Abstract Graph Neural Networks have emerged as a powerful paradigm for artificial intelligence driven drug discovery, offering molecular representation learning that surpasses many conventional approaches. Traditional ex...

Financial accountability in Indonesian BLU polytechnics — institutions managing State Budget allocations under Public Service Agency status — remains a persistent governance challenge. Recurring financial irregularit...

Abstract Background Family medicine provides comprehensive care by integrating biomedical, behavioral, and social sciences. While established in some sub-Saharan countries, it remains new and unintegrated in Tanzania’s...

JWST has revealed an abundance of low-luminosity active galactic nuclei (AGN) at high redshifts ( z  >  3), pushing the limits of black hole (BH) science in the early Universe. Results have claimed that these BHs are s...

Background Strengthening emergency care systems could reduce death and disability in low- and middle-income countries (LMICs), yet many struggle to provide timely, high-quality care. LMICs also face growing risks from cl...

Surface adhesion is critical to the survival of pathogenic bacteria both in natural niches and during infections, often via forming matrix-embedded communities called biofilms. Vibrio cholerae, the causal agent of pandem...

We conduct a search for strong gravitational lenses in the Dark Energy Survey (DES) Year 6 imaging data. We implement a pre-trained Vision Transformer (ViT) for our machine learning (ML) architecture and adopt interactiv...

Background: Health anxiety (HA) can cause significant distress in patients, leading to preoccupation with perceived illness and symptoms. Objective: This study examines the mediating roles of cognitive-emotional proces...

Abstract Black rhinoceros are critically endangered due to poaching in the wild (in situ). Globally, fewer than 200 animals are maintained as an ex situ insurance population. Unfortunately, the ex situ population faces m...

Abstract A growing body of evidence supports the role of nutrient sensing and metabolism pathways in regulating ageing rate and healthspan, but the diversity of human lifestyles challenges our ability to identify the mec...

Hypereosinophilic syndrome (HES) is characterized by blood or tissue hypereosinophilia leading to organ damage or dysfunction. HES is most commonly secondary or idiopathic, but may be primary (myeloid) or familial. Here,...

Abstract Memory representations contain a rich array of features, including perceptual and conceptual features of encoded stimuli. While prior research demonstrates that both feature types are independently represented i...

ABSTRACT Background and Aims Research to date has detailed numerous challenges and areas for potential harm surrounding medication management after hospital discharge for older adults, but few studies have directly detai...

Abstract Introduction Self-harm and suicide among young people are major public health concerns and delivering prevention and postvention support is crucial. Educational and youth organisations play a vital role in both ...

Introduction Early open fracture management aims to minimise the risk of complications. For the most severe open fracture wounds, multiple irrigation and debridement surgeries are required to overcome severe wound contam...

Galaxy is a widely used open-source platform for accessible, reproducible, transparent and scalable data analysis in the life sciences and beyond. Despite its growing adoption across domains, several misconceptions persi...

Hand dexterity assessments play a crucial role in informing the rehabilitative care of individuals with upper-limb hemiparesis. However, current assessments often struggle to evaluate the hand’s ability to precise...

This paper introduces Omega, the Ocean Model for E3SM Global Applications. Omega is a new ocean model designed to run efficiently on high performance computing (HPC) platforms, including exascale heterogeneous architect...