Buscar recursos académicos

In this study, healthy volunteers in Pakistan were asked to compare the single-dose pharmacokinetics of 16 mg of the angiotensin receptor blocker candesartan cilexetil following oral administration. Blood samples were ta...

Abstract This study aims to evaluate the nutritional significance of selected wild edible fruits from North-Eastern India through quantitative profiling of their free and total amino acid contents, thereby highlighting t...

Fractionation of the ethyl acetate soluble fraction from the ethanol extract of the leaves of Scutia buxifolia (Rhamnaceae) led to the isolation of quercetin, quercetin 3-0-rhamnoside (quercitrin), quercetin 3-0-glucosid...

A simple procedure was described for the determination of Withanolide A and Withanolide B in Ashwagandha root by HPLC. Separation was achieved on a Spherisorb C18 column with Water: Acetonitrile in the gradient elution. ...

A simple and sensitive HPLC method was validated for assessment of in vitro and in vivo recovery of gatifloxacin using microdialysis. The validation parameters of linearity, precision, accuracy and limit of detection wer...

Materias / palabras clave: Food; Composition; Sorbic acid; Alimento

Materias / palabras clave: Surface active agents; Ingeniería química

Melissa officinalis L., so called "Melissa" or "Toronjil", is a perennial aromatic herb, whose leaves are used in traditional medicine as a carminative, digestive and sedative, both in simple as in mixtures. Meanwhile, N...

Propylene glycol (PG), a generally recognized as safe ingredient widely used in pharmaceuticals, cosmetics, and food products, has not previously been investigated as a green solvent for high-performance liquid chromatog...

Abstract Background A sustainable and stability-indicating reversed-phase high-pressure liquid chromatography (RP-HPLC) method has been developed for the simultaneous estimation of chlorthalidone (CHL), Amlodipine (AML),...

"A rapid and sensitive analytical method for the trace determination of aflatoxin M1 in domestic waters was developed using chitosan as a sorbent and HPLC with fluorescence detection (HPLC-FLD). Computational simulations...

El Picosulfato de Sodio es un laxante indicado en el tratamiento del estreñimiento agudo y crónico. En este trabajo se adapta el método analítico por Cromatografía Líquida de Alta Resolución (CLAR), reportado en...

Comparative HPLC-UV and LC-MS/MS studies of impurity profiles of a reference sample (Xenical®, F. Hoffmann-La Roche Ltd., Switzerland) vs. generic (Lipiblock®, EMS-Sigma Pharma, a generic drug) were carried out with et...

En los últimos años hay un notable aumento de la demanda de fármacos con extractos vegetales estandarizados. Muchos de ellos, con indicación de actividad colagoga y colerética, contienen extracto de alcachofa. Con e...

A simple and rapid SPE-HPLC-DAD method was developed for the determination of 5-fluorouracil (5-FU) in surface samples. A C18 column (250 x 4.6 mm i.d., 5 µm) and a similar pre-column were used for the separation at 25...

Alpinia officinarum has been used by long time in the traditional medicine and several commercial extracts containing it are available on the market. In this paper a reversed phase high performance liquid chromatography-...

En el presente trabajo se desarrolló y validó un método por cromatografía líquida de alta eficacia (CLAE) para los estudios de disolución y la estimación cuantitativa de valdecoxib en tabletas y en el ingrediente ...

Fluconazol es un agente antifúngico triazólico sintético empleado en el tratamiento de la candidiasis y de otras infecciones fúngicas. Un método por cromatografía líquida de gran eficacia y un ensayo microbiológi...

A high performance liquid chromatography photo diode array UV detection electrospray ionization tandem mass spectrometry (HPLC-PDA-ESI/MSn) method was developed and validated for the quality evaluation of gamboge (dryed ...

A simple, specific, sensitive and validated RP-HPLC method for the simultaneous estimation of amlodipine (AMB) and valsartan (VAL) in marketed tablet formulation was developed. The analysis was carried out on a phenomene...

A reverse phase high-performance liquid chromatography-photodiode array detector (RP HPLC-DAD) method for simultaneous determination of lamivudine (3TC), zidovudine (AZT), two nucleoside reverse transcriptase inhibitors,...

A reproducible and selective method for the simultaneous determination of cyclophosphamide (CP) and ifosfamide (IF) in plasma has been developed and validated using isocratic elution. The assay is performed by HPLC-UV, w...

A simple reversed phase HPLC method was developed for simultaneous estimation of pioglitazone, glibenclamide, and glibenclamide impurities A and B from a combination drug product. The drugs and impurities are well separa...

Se ha desarrollado y validado un método de cromatografía líquida y espectrofotometría ultravioleta para la determinación de comprimidos de atenolol. La fase móvil empleada fue buffer acetato de amonio 10 mM (pH 7.0...