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102 resultados encontrados.

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Fabrication and optimization of floating tablets of antihypertensive drug losartan
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Fabrication and optimization of floating tablets of antihypertensive drug losartan
Sehrish Rana Rajpoot et al · AMMANIF · 2025 · ISSN 2521-0521
This study developed, optimized, and evaluated floating tablets containing Losartan potassium intended to provide prolonged gastric retention for hypertensive patients. HPMC K15M was found to effectively extend drug rele...
LCC TENDOlBoYXJtYWN5IGFuZCBtYXRlcmlhIG1lZGljYQ~~Idioma eng
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Phenolic and flavonoid content and in vitro inhibitory effect of some Amazonian fruit juices on CYP3A4 activity
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Phenolic and flavonoid content and in vitro inhibitory effect of some Amazonian fruit juices on CYP3A4 activity
Edna Márcia Almeida COSTA et al · Instituto Nacional de Pesquisas da Amazônia · 2022 · ISSN 0044-5967
ABSTRACT Many foods interact with drugs and may cause changes in the pharmacological effects of the co-administered therapeutic agent. The enzyme CYP3A4, which belongs to the cytochrome P450 enzyme complex, is responsibl...
LCC LCC:Science (General)Idioma eng
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A review on ethosomes as nanocarrier for skin delivery of drugs
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A review on ethosomes as nanocarrier for skin delivery of drugs
Khizra Mazhar et al · AMMANIF · 2024 · ISSN 2521-0521
Ethosomes are novel lipid and ethanolic phospholipid vesicles that are primarily employed for medication administration through the skin. These nanocarriers are designed to carry therapeutic delivery of drugs with varyin...
LCC TENDOlBoYXJtYWN5IGFuZCBtYXRlcmlhIG1lZGljYQ~~Idioma eng
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Multiclass Method for the Determination of Anthelmintic and Antiprotozoal Drugs in Livestock Products by Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry
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Multiclass Method for the Determination of Anthelmintic and Antiprotozoal Drugs in Livestock Products by Ultra-High-Performance Liquid Chromatography–Tandem Mass Spectrometry
Hyunjin Park et al · Springer Nature · 2023 · ISSN 2636-0772
Abstract The objective of this study was to establish a multi-residue quantitative method for the analysis of anthelmintic and antiprotozoal drugs in various livestock products (beef, pork, and chicken) using ultra-high-...
LCC TENDOkZvb2QgcHJvY2Vzc2luZyBhbmQgbWFudWZhY3R1cmU~; LCC:Animal cultureIdioma eng
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Compilation and testing of an emotion regulation scale for Muslim drug-addicted clients
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Compilation and testing of an emotion regulation scale for Muslim drug-addicted clients
Aristia Cotrunada Brsitumorang et al · Universitas PGRI Madiun · 2026 · ISSN 2477-5886
Every human being is endowed with emotions that can be well-controlled, as evidenced by the ability to regulate emotions. The gap relates to the understanding of emotional regulation in the context of drug addiction by a...
LCC TENDOkVkdWNhdGlvbg~~Idioma eng
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Effects of Antibiotics and Anti-Inflammatory Drugs on Enamel Development: A Systematic Review with Quantitative Synthesis
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Effects of Antibiotics and Anti-Inflammatory Drugs on Enamel Development: A Systematic Review with Quantitative Synthesis
Nadia Zamri et al · Elsevier · 2026 · ISSN 0020-6539
ABSTRACT: Objective: To investigate the effects of commonly prescribed antibiotics and nonsteroidal anti-inflammatory drugs (NSAIDs) during early life on enamel development through a systematic review with quantitative ...
LCC TENDOkRlbnRpc3RyeQ~~Idioma eng
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Enrichment, separation, and content determination of five effective components in liquorice root tablets by IER-CNTs combined with DLSPE-HPLC
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Enrichment, separation, and content determination of five effective components in liquorice root tablets by IER-CNTs combined with DLSPE-HPLC
GUO Xinying et al · The Editorial Office of Chinese Journal of Food Hygiene · 2025 · ISSN 1004-8456
ObjectiveTo establish a double-layer solid phase extraction and high performance liquid chromatography （DLSPE-HPLC） method for the simultaneous determination of five active components， including Liquiritin， Isogl...
LCC TENDOkZvb2QgcHJvY2Vzc2luZyBhbmQgbWFudWZhY3R1cmU~; LCC:Nutrition. Foods and food supplyIdioma zho
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Formulation, development and evaluation of buccoadhesive drug delivery system of risperidone
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Formulation, development and evaluation of buccoadhesive drug delivery system of risperidone
Namra Chaudhary et al · AMMANIF · 2023 · ISSN 2521-0521
Aim and Objective: The study aimed to manufacture Bucco-adhesive tablets of Risperidone and characterize the effectiveness of the drug by incorporating it into the mucoadhesive drug delivery system. The sustained release...
LCC TENDOlBoYXJtYWN5IGFuZCBtYXRlcmlhIG1lZGljYQ~~Idioma eng
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Moxidectin and ivermectin metabolic stability in sheep ruminal and abomasal contents
Artículo
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Moxidectin and ivermectin metabolic stability in sheep ruminal and abomasal contents
Lifschitz, Adrian Luis et al · Wiley Blackwell Publishing, Inc · 2005 · ISSN 0140-7783
The oral administration of macrocyclic lactones to sheep leads to poorer efficacy and shorter persistence of the antiparasitic activity compared to the subcutaneous treatment. Gastrointestinal biotransformation occurring...
Idioma eng
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QRNN-GRU framework for automatic argument and annotation extraction in medical drug reviews
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QRNN-GRU framework for automatic argument and annotation extraction in medical drug reviews
Eman Altameem et al · Nature Portfolio · 2026 · ISSN 2045-2322
Abstract Argument annotation in medical drug reviews is a challenging task due to noisy user-generated content, domain-specific terminology, and subjective expressions of medication efficacy and adverse effects. While ar...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Virulence factors, antimicrobial resistance, and plasmid content of Escherichia coli isolated in swine commercial farms Fatores de virulência, resistência aos antimicrobianos, presença de plasmídeos em Escherichia coli isoladas de amostras clínicas e ambientais de suínos
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Virulence factors, antimicrobial resistance, and plasmid content of Escherichia coli isolated in swine commercial farms Fatores de virulência, resistência aos antimicrobianos, presença de plasmídeos em Escherichia coli isoladas de amostras clínicas e ambientais de suínos
M.M. Costa et al · Universidade Federal de Minas Gerais, Escola de Veterinária · 2010 · ISSN 0102-0935
Virulence factors and antimicrobial resistance patterns of Escherichia coli isolates were evaluated. A total of 80 E. coli isolates were evaluated, being 64 from clinical samples (intestinal content and fragments of orga...
LCC LCC:Animal cultureIdioma eng
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An assessment of curcumin, curcumin spanlastics nanoparticles, and curcumin nanocrystals as possible drug delivery systems with antimicrobial, antioxidant, and antitumor activities
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An assessment of curcumin, curcumin spanlastics nanoparticles, and curcumin nanocrystals as possible drug delivery systems with antimicrobial, antioxidant, and antitumor activities
Jawza A. Almutairi et al · BMC · 2026 · ISSN 1472-6750
Abstract Background Curcumin is one such polyphenol that has low bioavailability as well as solubility. Therefore, the present study has analyzed, investigated, and estimated the antimicrobial, antioxidant, and anticance...
LCC TENDOkJpb3RlY2hub2xvZ3k~Idioma eng
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Controlling dispersion, stability and polymer content on PDEGMA-functionalized core-brush silica colloids
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Controlling dispersion, stability and polymer content on PDEGMA-functionalized core-brush silica colloids
Penelas, María Jazmín et al · Elsevier Science · 2019 · ISSN 0927-7757
Core-brush hybrid nanoparticles containing PEG surface functions are highly interesting as biologically inert and smart stimuli-responsive materials for future applications in biosensors, drug delivery, tissue engineerin...
Idioma eng
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Synthesis, characterization, and swelling behavior of new pH-sensitive hydrogels derived from copolymers of 2-hydroxyethyl methacrylate and 2-(diisopropylamino)ethylmethacrylate
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Synthesis, characterization, and swelling behavior of new pH-sensitive hydrogels derived from copolymers of 2-hydroxyethyl methacrylate and 2-(diisopropylamino)ethylmethacrylate
Faccia, Paula Andrea et al · John Wiley & Sons · 2012 · ISSN 1974-1980
The aim of this work was to synthesize and to characterize new pH-sensitive hydrogels that can be used in the controlled release of drugs, useful for dermal treatments or ophthalmology's therapies. Copolymers containing ...
Idioma eng
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Development and characterization of diacerein cream with curcuma longa having potent anti-inflammatory effect
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Development and characterization of diacerein cream with curcuma longa having potent anti-inflammatory effect
Muhammad Razi Ullah Khan · AMMANIF · 2024 · ISSN 2521-0521
Objective: Osteoarthritis, the most common type of arthritis, affects an increasing number of people and greatly diminishes their quality of life. Treatments for Osteoarthritis are divided into two categories: NSAIDs, wh...
LCC TENDOlBoYXJtYWN5IGFuZCBtYXRlcmlhIG1lZGljYQ~~Idioma eng
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Formulation and evaluation of diclofenac sodium microemulsion transdermal spray for rheumatoid arthritis
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Formulation and evaluation of diclofenac sodium microemulsion transdermal spray for rheumatoid arthritis
Laiba Shahid et al · AMMANIF · 2024 · ISSN 2521-0521
Background: The growth of a topical vehicle microemulsions has been more enhanced compared to the normal skin applications such as creams, gels among others. These micro-structured vehicles showed enhanced solubilization...
LCC TENDOlBoYXJtYWN5IGFuZCBtYXRlcmlhIG1lZGljYQ~~Idioma eng
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Formulation and evaluation of mucoadhesive gastro-retentive tablets of domperidone
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Formulation and evaluation of mucoadhesive gastro-retentive tablets of domperidone
Drakhshaan Abdullah et al · AMMANIF · 2024 · ISSN 2521-0521
Objective: This study was aimed at the formation and evaluation of the mucoadhesive gastro-retentive tablet of domperidone to overcome the drawbacks related to the oral administration of drugs. These gastro retentive for...
LCC TENDOlBoYXJtYWN5IGFuZCBtYXRlcmlhIG1lZGljYQ~~Idioma eng
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Formulation and evaluation of transdermal patch of lidocaine HCl for insect bite
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Formulation and evaluation of transdermal patch of lidocaine HCl for insect bite
Arjmand Mushtaq et al · AMMANIF · 2023 · ISSN 2521-0521
Objective: Lidocaine needs to be administered frequently as it has poor oral bioavailability and it lacks prolong duration of action thus the study was aimed at to devise, develop, and analyze a matrix system transdermal...
LCC TENDOlBoYXJtYWN5IGFuZCBtYXRlcmlhIG1lZGljYQ~~Idioma eng
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Pengaruh variasi berat polimer terhadap sifat fisik Patch NaF
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Pengaruh variasi berat polimer terhadap sifat fisik Patch NaF
Diyah Fatmasari et al · faculty of dentistry universitas gadjah mada · 2017 · ISSN 2460-0164
Influence of weight polymer variation towards sodium fluoride patch physical properties. Fluoride has been proven as a material for strengthen teeth. Many fluoride modalities are available nowadays, and the recent is sod...
LCC TENDOkRlbnRpc3RyeQ~~Idioma eng
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Anesthesia medication management competency in the post-anesthesia care unit: current challenges and strategies for enhancement—a qualitative study of nurses’ experiences
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Anesthesia medication management competency in the post-anesthesia care unit: current challenges and strategies for enhancement—a qualitative study of nurses’ experiences
Renqiang Lu et al · Frontiers Media S.A · 2026 · ISSN 2296-858X
ObjectivesWith the continuous increase in surgical volume in China and the relative shortage of anesthesiologists, anesthesia nurses (ANs) play an increasingly critical role in perioperative care, particularly in the Pos...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Automated reporter quantification in vivo: high-throughput screening method for reporter-based assays in zebrafish.
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Automated reporter quantification in vivo: high-throughput screening method for reporter-based assays in zebrafish.
Steven L Walker et al · Public Library of Science (PLoS) · 2012 · ISSN 1932-6203
Reporter-based assays underlie many high-throughput screening (HTS) platforms, but most are limited to in vitro applications. Here, we report a simple whole-organism HTS method for quantifying changes in reporter intensi...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Beyond spherical vesicles: morphological diversity of extracellular vesicles in health and disease
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Beyond spherical vesicles: morphological diversity of extracellular vesicles in health and disease
Manuel Adrián Velázquez-Cervantes et al · Taylor & Francis Group · 2026 · ISSN 0785-3890
Background The field of extracellular vesicles (EVs) has advanced considerably in recent years with new findings stemming from technical improvements in their isolation and characterization, expanding their potential as ...
LCC LCC:MedicineIdioma eng
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Binge-watching and substance use in adolescents: a cross-sectional study of behavioral risk factors and gender differences
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Binge-watching and substance use in adolescents: a cross-sectional study of behavioral risk factors and gender differences
Jorge Becerra-Arroyo et al · BMC · 2026 · ISSN 2050-7283
Abstract Background Problematic binge-watching, defined as the compulsive consumption of audiovisual content for prolonged periods of time, has increased in prevalence, especially among adolescents. However, its relation...
LCC TENDOlBzeWNob2xvZ3k~Idioma eng
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Bioavailability of in-feed tetracyclines is influenced to a greater extent by crude protein rather than calcium
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Material complementario disponible Artículo Universidad de Costa Rica
Bioavailability of in-feed tetracyclines is influenced to a greater extent by crude protein rather than calcium
Granados Chinchilla, Fabio et al · Universidad de Costa Rica · 2018 · ISSN 0377-8401
Feed is a common vehicle for tetracycline administration in animal farming. However, veterinarians and farmers often overlook that common feed components, such as proteins and calcium, may interact with these drugs and t...
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