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109 resultados encontrados.

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Drug Delivery
Artículo
Acceso abierto Artículo DOAJ
Drug Delivery
Taylor & Francis Group; United Kingdom · ISSN 1071-7544
Materias / palabras clave: drug delivery systems, drug targeting, pharmaceutical sciences; Medicine: Therapeutics. Pharmacology
Idioma English
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A comprehensive review of nanotechnology based drug delivery systems for osteoarthritis treatment
Artículo
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A comprehensive review of nanotechnology based drug delivery systems for osteoarthritis treatment
Adikari Clawdia et al · De Gruyter · 2026 · ISSN 2191-9097
The complex etiology and short-term positive effects of treatments for osteoarthritis (OA) remain a significant challenge globally. The lack of approved disease-modifying OA drugs (DMOADs) and the rapid clearance of intr...
LCC TENDOlRlY2hub2xvZ3k~; TENDOkNoZW1pY2FsIHRlY2hub2xvZ3k~; TENDOlBoeXNpY2FsIGFuZCB0aGVvcmV0aWNhbCBjaGVtaXN0cnk~Idioma eng
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Formulation and evaluation of self-emulsifying drug delivery system (SEDDS) for nevirapine
Artículo
Acceso abierto Artículo DOAJ
Formulation and evaluation of self-emulsifying drug delivery system (SEDDS) for nevirapine
Sana Shahzad et al · AMMANIF · 2025 · ISSN 2521-0521
This study focuses on the development and optimization of a self-emulsifying drug delivery system (SEDDS) for Nevirapine, a BCS Class II non-nucleoside reverse transcriptase inhibitor (NNRTI) used in HIV therapy. Our obj...
LCC TENDOlBoYXJtYWN5IGFuZCBtYXRlcmlhIG1lZGljYQ~~Idioma eng
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Recent Advances in Novel Drug Delivery Systems for the Management of Cutaneous Squamous Cell Carcinoma
Artículo
Acceso abierto Artículo DOAJ
Recent Advances in Novel Drug Delivery Systems for the Management of Cutaneous Squamous Cell Carcinoma
Fu X et al · Dove Medical Press · 2026 · ISSN 1178-2013
Xiaoyi Fu,1 Zijian Zhang,1 Qinyi Dong,1 Siying Li,2 Xinman Wang,2 Han Zhang,2 Jiahao Bai,2 Huiyan Han,2 Lei Shi,2 Kaili Zheng,2 Lili Liang2,3 1The Third Clinical College, Shanxi University of Chinese Medicine, Taiyuan, S...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma eng
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Recent advances in application of hydrogel-based nanomaterials in breast cancer: from drug delivery, immunotherapy mechanisms to clinical applications
Artículo
Material complementario disponible Artículo DOAJ
Recent advances in application of hydrogel-based nanomaterials in breast cancer: from drug delivery, immunotherapy mechanisms to clinical applications
Yuanbing Xu et al · BMC · 2026 · ISSN 1477-3155
Abstract Breast cancer remains one of the most prevalent malignant tumors affecting women worldwide and continues posing a major threat to global health. Current clinical treatments include surgery, chemotherapy, radioth...
LCC TENDOkJpb3RlY2hub2xvZ3k~; TENDOk1lZGljYWwgdGVjaG5vbG9neQ~~Idioma eng
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Surface-modified nanocarriers in the design of targeted drug delivery systems for parasitic diseases: a comprehensive review
Artículo
Acceso abierto Artículo DOAJ
Surface-modified nanocarriers in the design of targeted drug delivery systems for parasitic diseases: a comprehensive review
Chinekwu S. Nwagwu et al · BMC · 2026 · ISSN 2661-801X
Abstract Parasitic diseases such as malaria, leishmaniasis, and schistosomiasis remain difficult to treat due to the pathogens’ complex life cycles, intracellular niches, and resistance to conventional therapies. Tradi...
LCC TENDOkNoZW1pc3RyeQ~~Idioma eng
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Microneedles drug delivery system: insights on its fabrication techniques and challenges
Artículo
Acceso abierto Artículo DOAJ
Microneedles drug delivery system: insights on its fabrication techniques and challenges
Abdul Rehman · AMMANIF · 2024 · ISSN 2521-0521
In recent years, there has been significant interest in an innovative transdermal delivery technology. This technology has the ability to distribute therapeutics and cosmeceuticals for various applications, such as vacci...
LCC TENDOlBoYXJtYWN5IGFuZCBtYXRlcmlhIG1lZGljYQ~~Idioma eng
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Functionalized bridged silsesquioxane-based nanostructured microspheres: Performance as novel drug-delivery devices in bone tissue-related applications
Artículo
Acceso abierto Artículo CONICET Digital
Functionalized bridged silsesquioxane-based nanostructured microspheres: Performance as novel drug-delivery devices in bone tissue-related applications
Romeo, Hernan Esteban et al · Sage Publications Ltd · 2012 · ISSN 0885-3282
Two kinds of functionalized nanostructured hybrid microspheres, based on the bridged silsesquioxane family, were synthesized by employing the sol-gel method via self-assembly of two different organic-inorganic bridged mo...
Idioma eng
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Smart nanomaterials enabling drug delivery and glucose monitoring for diabetes management
Artículo
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Smart nanomaterials enabling drug delivery and glucose monitoring for diabetes management
Meenaloshini Gopalakrishnan et al · Springer · 2026 · ISSN 2731-9229
Abstract Diabetes mellitus represents one of the most prevalent chronic diseases worldwide, posing serious challenges to global health and healthcare sustainability. Conventional therapeutic strategies often face limitat...
LCC LCC:Materials of engineering and construction. Mechanics of materialsIdioma eng
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Hydrogel-based solid dispersion: development of sustained release drug delivery for aceclofenac indicated for the relief of pain and inflammation
Artículo
Material complementario disponible Artículo DOAJ
Hydrogel-based solid dispersion: development of sustained release drug delivery for aceclofenac indicated for the relief of pain and inflammation
Sana Shahzad et al · AMMANIF · 2025 · ISSN 2521-0521
Developing aceclofenac hydrogel-based solid dispersions enclosed in two modified gelatin capsules for long-term medication delivery was the aim of this study. Eudragit L 100 and hydroxypropyl methylcellulose acetate succ...
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Phage enabled precision drug delivery: dual function platforms for therapeutics and genetic cargo transport
Artículo
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Phage enabled precision drug delivery: dual function platforms for therapeutics and genetic cargo transport
Md. Sharifull Islam et al · Frontiers Media S.A · 2026 · ISSN 1664-302X
The rising concern of antimicrobial resistance, coupled with the continually challenging management of complicated diseases such as cancer, has provided momentum toward precision molecular medicine. This review provides ...
LCC TENDOk1pY3JvYmlvbG9neQ~~Idioma eng
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Modeling of drug delivery from erodible and non-erodible laminated planar devices into a finite external medium
Artículo
Acceso abierto Artículo CONICET Digital
Modeling of drug delivery from erodible and non-erodible laminated planar devices into a finite external medium
Helbling, Ignacio Marcelo et al · Elsevier Science · 2010 · ISSN 0376-7388
Analytical solutions based on the pseudo-steady state approximation (PSSA) were derived for the case of controlled dispersed-drug release from erodible and non-erodible planar matrices, through a membrane, and taking int...
Idioma eng
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Dual-stiffness nanoparticles for compartment-specific drug delivery in stroke
Artículo
Acceso abierto Artículo DOAJ
Dual-stiffness nanoparticles for compartment-specific drug delivery in stroke
Hui Liu et al · Nature Portfolio · 2026 · ISSN 2041-1723
Abstract Ischemic stroke presents a dual therapeutic challenge, involving dynamic and compartmentalized pathology in both the peripheral immune system and the central nervous system. Departing from conventional holistic ...
LCC TENDOlNjaWVuY2U~Idioma eng
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Formulation, development and evaluation of buccoadhesive drug delivery system of risperidone
Artículo
Material complementario disponible Artículo DOAJ
Formulation, development and evaluation of buccoadhesive drug delivery system of risperidone
Namra Chaudhary et al · AMMANIF · 2023 · ISSN 2521-0521
Aim and Objective: The study aimed to manufacture Bucco-adhesive tablets of Risperidone and characterize the effectiveness of the drug by incorporating it into the mucoadhesive drug delivery system. The sustained release...
LCC TENDOlBoYXJtYWN5IGFuZCBtYXRlcmlhIG1lZGljYQ~~Idioma eng
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Bioavailability enhancement of sulpiride by self-microemulsifying drug delivery system
Artículo
Acceso abierto Artículo SEDICI UNLP
Bioavailability enhancement of sulpiride by self-microemulsifying drug delivery system
Chitneni, Mallikarjun et al · SEDICI UNLP · 2010
The self-microemulsifying drug delivery system (SMEDDS) was employed to improve the bioavailability of sulpiride, a drug which is poorly soluble. The mean droplet size and emulsification time of the test formulation us...
Idioma en
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Formulation development and evaluation of thermosensitive gel for vaginal drug delivery
Artículo
Acceso abierto Artículo SEDICI UNLP
Formulation development and evaluation of thermosensitive gel for vaginal drug delivery
Bhat, Sudeendra R. et al · SEDICI UNLP · 2010
A new reversible thermosensitive drug delivery system was designed and prepared by using chitosan and glycerophosphate with or without poly (ethylene glycol) and used as an a carrier for the Miconazole nitrate, an antifu...
Idioma es
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In vitro and In vivo toxicology evaluation to determine suitable biomedical Polymers for development of a papain-containing drug delivery system
Artículo
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In vitro and In vivo toxicology evaluation to determine suitable biomedical Polymers for development of a papain-containing drug delivery system
Alcântara, Mara T. S. et al · SEDICI UNLP · 2011
Papain has been known by many decades for wounded tissues repair. However, papain stability is not high enough to be commercialized in a stable pharmaceutical form; therefore its use is limited. The strategy to entrap pa...
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Natural composites and nanocomposites for drug delivery
Libro electrónico
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Natural composites and nanocomposites for drug delivery
Benedini, Luciano Alejandro et al · Elsevier · 2026
Synthesis of new drugs, their rational design, or isolation from natural sources has decreased, and these facts lead to the use of currently marketed drugs. Some of them, extensively used, show unfavorable properties rel...
Idioma eng
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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1
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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1
Christopher A. Lipinski; Franco Lombardo; Beryl W. Dominy; Paul J. Feeney · Advanced Drug Delivery Reviews · 2001
Materias / palabras clave: Solubility; Drug discovery; Thermodynamics; Chemistry; Permeability (electromagnetism); Computational chemistry; Physics; Organic chemistry; Membrane; Biochemistry
Idioma en
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Biphasic gastroretentive drug delivery system of acyclovir: formulation and in vitro evaluation
Artículo
Material complementario disponible Artículo SEDICI UNLP
Biphasic gastroretentive drug delivery system of acyclovir: formulation and in vitro evaluation
Bandari, Suresh et al · SEDICI UNLP · 2010
A biphasic gastroretentive drug delivery system of acyclovir consisted of loading dose tablet and floating multiple matrix tablets was prepared by direct compression process. The delivery system was designed by hydroxy...
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Chronomodulated rupturable pulsatile drug delivery of theophylline: preparation and in vitro characterization
Artículo
Material complementario disponible Artículo SEDICI UNLP
Chronomodulated rupturable pulsatile drug delivery of theophylline: preparation and in vitro characterization
Mahajan, Ashok N. et al · SEDICI UNLP · 2010
The aim of the present study was to develop and evaluate chronomodulated rupturable pulsatile drug delivery of theophylline for the treatment of nocturnal asthma. Core tablets containing theophylline were coated with t...
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Gastroretentive drug delivery system of captopril and hydrochlorothiazide bilayer tablet: formulation, optimization and in vivo evaluation
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Gastroretentive drug delivery system of captopril and hydrochlorothiazide bilayer tablet: formulation, optimization and in vivo evaluation
Wadekar, Sharadchandra B. et al · SEDICI UNLP · 2011
The purpose of the present study was to develop and optimize floating-bioadhesive bilayer gastroretentive drug delivery system (GRDDS) exhibiting a unique combination of floatation and bioadhesion to prolong residence ...
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Irbesartan loaded self emulsifying drug delivery system: pseudoternary phase diagram, formulation, characterization and in vitro dissolution studies
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Irbesartan loaded self emulsifying drug delivery system: pseudoternary phase diagram, formulation, characterization and in vitro dissolution studies
Haque, Tasnuva et al · SEDICI UNLP · 2010
A self-emulsifying drug delivery system (SEDDS) of a poorly water soluble drug, irbesartan (IRB), was designed. The aim was to improve the solubility as well as dissolution rates of IRB. Solubility of IRB in different ...
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Preparation and evaluation of lithium carbonate loaded PEA microspheres for controlled drug delivery
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Preparation and evaluation of lithium carbonate loaded PEA microspheres for controlled drug delivery
Malure, Manjunath et al · SEDICI UNLP · 2011
The goal of any drug delivery system is to provide a therapeutic amount of drug (s) to the proper site in the body in order to promptly achieve and there by to maintain the desired drug concentrations during treatment. T...
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