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Renal transplantation is the most prominent treatment of end-stage renal failure. Unfortunately, acute and chronic rejections and drug toxicities reduce graft survival in the post-transplantation period. An attempt has t...

Solid organ transplant patients have higher suicide rates compared to the general population. It is suggested that the major factor contributing to this is to be on multiple immunosupressive drugs, with some of these dru...

Nonsteroidal anti-inflammatory drugs and paracetamol (acetaminophen) which are analgesic-antipyretic drugs are thought to be safe and are most commonly used in children to control pain and fever. We retrospectively an...

Patients with chronic kidney disease may show altered pharmacokinetics and pharmacodynamic responses to many drugs in comparison to patients with normal renal function. Therefore, effective and safe drug usage is difficu...

Heavy proteinuria and nephrotic syndrome may occur in association with a wide variety of primary and systemic diseases and also with drugs. Major drugs that can induce nephrotic syndrome and glomerular damage are gold, p...

Type II diabetic 32 patients (21 F, 11 M; aged 54 ±8 years) with mild-moderate hypertensive and persistent microalbuminuric were enrolled to the study. The diagnosis of diabetes had been done at least 5 years ago and th...

Hypervolemia and uremic toxins result in accelerated atherosclerosis in chronic renal failure by causing endothelial dysfunction hypertension. The vast majority of patients undergoing renal replacement therapy are hypert...

Uremia affects thyroid functions and hypothyroidism occurs in end-stage renal disease (ESRD) patients. However, thyrotoxicosis occurs in ESRD patients rarely. Most of the published reports about thyrotoxicosis in ESRD pa...