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82 resultados encontrados.

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Gene Expression of Antioxidant Enzymes in Healthy and Aborted Women
Artículo
Acceso abierto Artículo DOAJ
Yasir A'al-Issa et al · University of Mosul, College of Education for Pure Science · 2025 · ISSN 1812-125X
Gene expression analysis is one of the most important tools for discovering the link between human disorders and the genes that control them. The primary purpose of this study is to identify the gene expression profile o...
LCC TENDOkVkdWNhdGlvbg~~; LCC:Science (General)Idioma eng
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Open Access
Gene Therapy Using Recombinant Adeno-Associated Virus for Leber Congenital Amaurosis Induced by RPE65 Mutation
Artículo
Material complementario disponible Artículo DOAJ
Owliaee I et al · Dove Medical Press · 2026 · ISSN 1177-5483
Iman Owliaee,1 Ali Teimoori,1 Mohammad Shoushtari,2 Ali Shojaeian3 1Department of Medical Virology, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran; 2Department of Virology, Pasteur Institute o...
LCC TENDOk9waHRoYWxtb2xvZ3k~Idioma eng
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Genetic aspects of sleep in humans
Artículo
Acceso abierto Artículo DOAJ
Camila Guindalini et al · Thieme Revinter Publicações Ltda · 2012 · ISSN 1984-0659
Together with the environment, genetic factors can significantly influence sleep and its architecture. Monozygotic twins have greater similarity in terms of latency and duration of sleep cycles than dizygotic twins, in a...
LCC TENDOlBzeWNob2xvZ3k~; TENDOkNvbnNjaW91c25lc3MuIENvZ25pdGlvbg~~Idioma eng
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Open Access
Haloperidol versus second-generation antipsychotics on the cognitive performance of individuals with schizophrenia and related disorders: pairwise meta-analysis of randomized controlled trials
Artículo
Acceso abierto Artículo DOAJ
Daniel Prates Baldez et al · Associação de Psiquiatria do Rio Grande do Sul · 2025 · ISSN 2238-0019
Abstract Objective Despite previous literature, the superiority of second-generation antipsychotics (SGAs) relative to first-generation antipsychotics – especially haloperidol – on cognitive management in schizophre...
LCC TENDOlBzeWNoaWF0cnk~Idioma eng
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Open Access
Insulin Resistance Across Cerebrovascular and Related Disorders: Mechanisms, Measurement, Genetics, and Clinical Implications
Artículo
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Chen K et al · Dove Medical Press · 2026 · ISSN 1178-2021
Kai Chen,1,* Yiqing Nong,1,* Ying Liu,2 Ziming Ye3 1Department of Neurology, Guangxi Medical University Kaiyuan Langdong Hospital, Nanning, 530023, People’s Republic of China; 2Department of Rehabilitat...
LCC LCC:Neurosciences. Biological psychiatry. Neuropsychiatry; LCC:Neurology. Diseases of the nervous systemIdioma eng
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Oral health-related quality of life in adult inpatients with psychiatric and/or substance use disorders: a Norwegian cross-sectional study
Artículo
Material complementario disponible Artículo DOAJ
Kristina G. Kantola et al · Frontiers Media S.A · 2026 · ISSN 2673-4842
IntroductionThis study aimed to assess the prevalence and nature of oral health impacts on daily life and examine the relationship between psychiatric symptoms, oral health problems, and oral health related quality of li...
LCC TENDOkRlbnRpc3RyeQ~~Idioma eng
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Analysis of risk factors for tic disorders in children in Hubei region based on liquid chromatography-tandem mass spectrometry
Artículo
Material complementario disponible Artículo DOAJ
Yingchan Hao et al · Frontiers Media S.A · 2026 · ISSN 1662-453X
ObjectiveThis study aims to investigate the correlation between trace element concentrations, 25-hydroxyvitamin D [25(OH)D] levels, and the severity of tic disorders (TD) in children from the Hubei region. Additionally, ...
LCC LCC:Neurosciences. Biological psychiatry. NeuropsychiatryIdioma eng
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Case Report: Where is the boundary between autosomal recessive early-onset Parkinson’s disease and dystonia-parkinsonism: a case of PLA2G6-associated neurodegeneration
Artículo
Acceso abierto Artículo DOAJ
Xiao-Tian Li et al · Frontiers Media S.A · 2026 · ISSN 1662-5161
BackgroundMutations in the PLA2G6 gene cause a spectrum of neurodegenerative disorders, with autosomal recessive early-onset Parkinson’s disease (AREP) and dystonia-parkinsonism (DP) representing the two primary subtyp...
LCC LCC:Neurosciences. Biological psychiatry. NeuropsychiatryIdioma eng
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Open Access
Characterizing the effects of genetic liability to autoimmune conditions on pregnancy outcomes using Mendelian randomization
Artículo
Acceso abierto Artículo DOAJ
Elisabeth Aiton et al · BMC · 2026 · ISSN 1741-7015
Abstract Background Autoimmune conditions are common in women of reproductive age. They are associated with an increased risk of adverse pregnancy outcomes; whether this is causal is unclear. Our aim was to explore the c...
LCC LCC:MedicineIdioma eng
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Open Access
Common mental disorders in mothers vs. infant and obstetric outcomes: a review Transtornos mentais comuns em mães versus desfechos infantis e obstétricos: uma revisão
Artículo
Material complementario disponible Artículo DOAJ
Paula Borba et al · Associação de Psiquiatria do Rio Grande do Sul · 2012 · ISSN 2237-6089
INTRODUCTION: Pregnancy has been shown to increase women’s vulnerability to mental disorders. Common mental disorders (CMDs) have been studied both in the general population and in pregnant vs. non-pregnant women. ...
LCC TENDOlBzeWNoaWF0cnk~Idioma eng
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Differential Analysis of Personality Disorders and Affective Disorders
Artículo
Material complementario disponible Artículo DOAJ
Yuliia Zinchenko · V. N. Karazin Kharkiv National University · 2025 · ISSN 2225-7756
The article considers the problem of differential differences between severe personality disorders and affective spectrum disorders. A comparative analysis of symptoms, behavioral manifestations, and features of the deve...
LCC TENDOlBzeWNob2xvZ3k~Idioma ukr
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Hemophilia in Women: Beyond the Carrier State - Clinical, Genetic, and Diagnostic Challenges
Artículo
Acceso abierto Artículo DOAJ
Sylwia Haba et al · Nicolaus Copernicus University in Toruń · 2026 · ISSN 2450-3118
Background: Hemophilia is a genetic bleeding disorder resulting from a deficiency of specific coagulation factors. The most common forms, hemophilia A and B, are X-linked and mainly affect males, with females usually bei...
LCC TENDOlNwb3J0cw~~; TENDOlNwb3J0cyBtZWRpY2luZQ~~Idioma eng
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Open Access
Prevalence of Abortifacient Disorders in Small Ruminants: a Comprehensive Review
Artículo
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Abdul Saboor et al · Wright State University · 2024 · ISSN 2309-3854
Abortifacient disorders in small ruminants present a serious problem for livestock farmers, leading to financial losses and lower production rates. This review examines both infectious and non-infectious factors that cau...
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Open Access
Prior stress promotes the generalization of contextual fear memories: Involvement of the gabaergic signaling within the basolateral amygdala complex
Artículo
Acceso abierto Artículo CONICET Digital
Bender, Crhistian Luis et al · Pergamon-Elsevier Science Ltd · 2018 · ISSN 0278-5846
Fear generalization occurs when a response, previously acquired with a threatening stimulus, is transferred to a similar one. However, it could be maladaptive when stimuli that do not represent a real threat are appraise...
Idioma eng
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Open Access
Psychiatric disorders, depression and quality of life in patients with psychogenic non-epileptic seizures and drug resistant epilepsy living in Argentina
Artículo
Material complementario disponible Artículo CONICET Digital
Scévola, Maria Laura et al · W B Saunders Co Ltd · 2021 · ISSN 1059-1311
Objectives: Psychiatric disorders are frequently found in both patients with PNES and DRE, making the differential diagnosis even more complex. The aim of this study was to analyze and compare psychiatric aspects and the...
Idioma eng
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Relationship between psychopathology and binge size in binge eating spectrum disorders
Artículo
Acceso abierto Artículo DOAJ
Carla L. Mourilhe Silva et al · Associação de Psiquiatria do Rio Grande do Sul · 2024 · ISSN 2238-0019
Abstract Objective: Food intake during binge eating episodes (BEE) has been found to be associated with symptoms of depression and anxiety in individuals with eating disorders (EDs). The objective of this study was to e...
LCC TENDOlBzeWNoaWF0cnk~Idioma eng
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Open Access
Shift work disorders: implications and proposed management
Artículo
Acceso abierto Artículo DOAJ
Patrick Rademaker Burke et al · Thieme Revinter Publicações Ltda · 2012 · ISSN 1984-0659
Economic demand has modified the temporal organization of work and established the system of shift work. The inability of the individual worker to maintain an adequate quantity and quality of sleep after a day of shift w...
LCC TENDOlBzeWNob2xvZ3k~; TENDOkNvbnNjaW91c25lc3MuIENvZ25pdGlvbg~~Idioma eng
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Open Access
Temporomandibular disorders prevalence and associated factors among adolescents in Al-Ahsa, Saudi Arabia: a school-based cross-sectional study
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Jasem Ahmad H Alburaih et al · BMC · 2026 · ISSN 1472-6831
Abstract Background Temporomandibular disorders (TMDs) are conditions affecting the temporomandibular joint and its surrounding structures, characterized by common clinical symptoms. Therefore, this study aimed to identi...
LCC TENDOkRlbnRpc3RyeQ~~Idioma eng
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The emerging role of gene therapy in autism spectrum disorder
Artículo
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Marzieh Shokoohi et al · Springer · 2026 · ISSN 2731-4383
Abstract Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by heterogeneity in its genetic, epigenetic, and environmental etiologies, posing significant challenges for therapeutic development...
LCC LCC:Neurosciences. Biological psychiatry. NeuropsychiatryIdioma eng
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Open Access
The landscape of 605 genetically confirmed distinct rare diseases in a single center in Mexico (2005–2025)
Artículo
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Juan Carlos Zenteno et al · BMC · 2026 · ISSN 1750-1172
Abstract Background Timely diagnosis and therapeutic management of rare diseases (RDs) are greatly hampered by limited clinical information and a lack of reliable epidemiological data. RDs constitute a heterogeneous grou...
LCC LCC:MedicineIdioma eng
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Open Access
The role of sleep disorders in the motoric and cognitive trajectories of older physically frail sarcopenic and healthy active subjects: SOMNUS-DARE, a prospective cohort study
Artículo
Material complementario disponible Artículo DOAJ
Marco Salvi et al · BMC · 2026 · ISSN 1471-2318
Abstract Background Sarcopenia, altered bone and systemic metabolism, physical frailty and cognitive decline are age-dependent and interrelated phenomena. Sleep disorders which are erroneously considered as part of the a...
LCC TENDOkdlcmlhdHJpY3M~Idioma eng
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Viral vector research in human gene therapy: Basic principles, alternative evaluation models, and clinical applications
Artículo
Material complementario disponible Artículo DOAJ
Julia Hurnikova et al · Elsevier · 2026 · ISSN 2472-6303
Gene therapy holds a great potential for treating a variety of human disorders by introducing foreign therapeutic genetic material into target cells using gene carriers (vectors). Most particularly, viral vectors show a ...
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A novel duplication frameshift mutation in the BAG3 gene in a patient with dilated cardiomyopathy
Artículo
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Wei Zhang et al · BMC · 2026 · ISSN 1471-2261
Abstract Background/Objectives Dilated cardiomyopathy (DCM) is characterized by heart failure and cardiac dilation, distinguishing it from ischemic and non-ischemic heart diseases. To date, more than 50 genes have been i...
LCC TENDOkRpc2Vhc2VzIG9mIHRoZSBjaXJjdWxhdG9yeSAoQ2FyZGlvdmFzY3VsYXIpIHN5c3RlbQ~~Idioma eng
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Cardiovascular, respiratory, and related disorders: Key messages from Disease Control Priorities, 3rd edition
Artículo
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Prabhakaran, Dorairaj et al · Elsevier Science Inc · 2018 · ISSN 1224-1236
Cardiovascular, respiratory, and related disorders (CVRDs) are the leading causes of adult death worldwide, and substantial inequalities in care of patients with CVRDs exist between countries of high income and countries...
Idioma eng
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Open Access