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Abstract Glaucoma is the second-highest cause of blindness and the leading cause of irreversible blindness worldwide. Most people with glaucoma are not aware that they have a sight-threatening condition. People of Africa...

BackgroundPhakic intraocular lenses (pIOLs), used to correct high refractive errors, have since been associated with long-term complications including glaucoma and cataract formation. Elevated intraocular pressure (IOP) ...

ABSTRACT Retinal ganglion cell (RGC) degeneration represents a cardinal etiology of irreversible vision loss in glaucoma, where efficacious regenerative therapies remain scarce. RGC replacement therapy holds promise for ...

Objective. To evaluate the relationship between ophthalmic hemodynamic parameters, particularly the rheographic coefficient (RQ), and the activity of iris neovascularization in neovascular glaucoma (NVG) of different eti...

Abstract Glaucoma trabecular meshwork (GTM) cells cultured in vitro retain many characteristics of their in situ phenotype. Here, we used isobaric tandem mass tags (TMTpro) to label peptides from glaucomatous and non-gla...

Abstract This study aims to identify new genetic loci associated with primary open-angle glaucoma (POAG) and explore shared genetic risk factors across African, European, and Admixed American/Latino populations. Genome-w...

Phacolytic glaucoma is a rare type of secondary open-angle glaucoma caused by leakage of high-molecular-weight lens proteins through an intact capsule of a mature/hypermature cataract. It is most frequently seen in elder...

Abstract Background To evaluate the risk of Retinal Artery Occlusion (RAO) in individuals with Primary-Open Angle Glaucoma (POAG) using a large-scale real-world database. Methods This retrospective cohort study used the ...

ABSTRACT Background and Aims In Ethiopia, glaucoma and related cases account for 5.2% of the irreversible blindness and is the fifth main cause of blindness. The aim of this study was to investigate the time to blindness...

Abstract Backgrounds Acute primary angle-closure glaucoma (APACG) and chronic primary angle-closure glaucoma (CPACG) exhibit distinct clinical features, yet the molecular mechanisms underlying their differing progression...

Zoltan Z Nagy,1 Kinga Kranitz,1 Iqbal Ike K Ahmed,2,3 Ticiana De Francesco,2,4 Eric Mikula,5,6 Tibor Juhasz5–7 1Department of Ophthalmology, Semmelweis University, Budapest, Hungary; 2John Moran Eye Center, Uni...

Abstract Background Our objective is to investigate the association between prospectively-reported and retrospectively-reported falls data and the likelihood of subsequent falls in a cohort of patients with and without v...

Abstract Purpose This study introduces a new Convolutional Neural Network (CNN) architecture, EyeDiagNet, for the classification of fundus images into four classes: normal, cataract, diabetic retinopathy (DR), and glauco...

Yamato Katsura,* Hisataka Fujimoto,* Masashi Takata, Hiroshi Yokoyama, Tomohiro Sekiya, Fumi Gomi Department of Ophthalmology, Hyogo Medical University, Nishinomiya, Hyogo, Japan*These authors con...

Artificial intelligence (AI) has emerged as a transformative force in modern ophthalmology, enabling rapid advances in disease detection, clinical decision support, workflow optimization, and tele-ophthalmology. Ophthalm...

BackgroundLycium barbarum glycopeptide (LbGp) has been reported to exert neuroprotective effects, yet its role in chronic ocular hypertension (COH) and the underlying mechanisms remain unclear. This study investigated wh...

Abstract Accurate anterior-segment assessment is essential for detecting conditions such as primary angle-closure glaucoma, cataract, and keratoconus, yet current tools remain limited: slit-lamp biomicroscopy is qualitat...

Abstract High myopia can lead to cataract, glaucoma, retinal detachment, choroidal neovascularisation, and macular degeneration, causing irreversible vision loss. Imaging detects these complications, but population scree...