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Background: Kaposi sarcoma (KS) remains the most common HIV-associated malignancy in South Africa and continues to contribute substantially to the national disease burden, despite the widespread availability of antiretr...

Background HIV is a major health challenge in Kenya, where prevalence exceeds global averages. Achieving viral suppression depends on consistent adherence to antiretroviral therapy (ART), but individuals in neighbourhood...

ObjectiveThis study seeks to trace the source of HIV infection in a male adolescent (P1) with a newly recognized heterosexual orientation in Zhejiang Province on August 23, 2019.MethodsAn in-depth epidemiological intervi...

Abstract Background Trauma is among the leading causes of death and disability in Malawi and accounts for a substantial proportion of emergency admissions at tertiary hospitals. However, injured patients presenting for t...

IntroductionThe integration of tuberculosis (TB) preventive treatment (TPT) into HIV services through electronic health records (EHR) can improve outcomes by enhancing care coordination, reducing redundancies, and suppor...

Resumo Objetivo Realizar a adaptação transcultural e avaliação psicométrica do questionário Brief Estimate of Health Knowledge and Action (BEHKA)—HIV Version para uso no Brasil. Métodos Estudo psicométrico ...

Abstract Background Vertical transmission is the main mode of acquisition of HIV infection in the Democratic Republic of Congo (DRC). We aimed to determine the factors associated with the serological status of mothers an...

Background: HIV is the most common cause of secondary thrombotic thrombocytopenic purpura (TTP) in South Africa.  Objectives: To assess the clinical presentations and outcomes of patients treated for HIV-associated and...

Abstract Background Prophylactic medications are commonly used to prevent tuberculosis and opportunistic infections in people living with HIV (PLWH) who are on first-line antiretroviral therapy (ART). However, their cumu...

ABSTRACT Background and Aim Cytopenias remain among the most frequent hematologic complications of HIV infection, affecting treatment outcomes and quality of life. The introduction of highly active antiretroviral therapy...

Abstract Background Cryptosporidium spp. is an important intestinal protozoan parasite causing morbidity and mortality in immunocompromised patients, particularly those with HIV+/AIDS. A cross-sectional study was conduct...

Despite widespread rollout of dolutegravir-based (DTG) antiretroviral therapy (ART) in East Africa, viral non-suppression, advanced HIV disease (AHD), and multimorbidity persist, reflecting gaps in service response rathe...

Recent changes in the global health financing resulted in a steep reduction in donor support for HIV programmes worldwide, threatening years of progress in reducing infections and mortality. These developments require ex...

Abstract Background High-throughput sequencing (HTS) enables the detection of low-frequency HIV-1 drug resistance mutations (DRMs) that are often missed by conventional Sanger sequencing. However, the clinical implementa...

Abstract Introduction Dolutegravir-based antiretroviral therapy (ART), a key component of HIV treatment in low- and middle-income countries, has been associated with weight gain and increased adiposity in people living w...

Abstract Background Understanding the genetic evolution of HIV-1 Transmitted/Founder (T/F) virus is crucial for developing effective treatment and prevention strategies due to its rapid mutation and recombination rates. ...

Abstract Background Immunological non-responders (INR), distinguished by profound immune dysfunction, fail to achieve immune reconstitution despite receiving antiretroviral therapy (ART). INR experience lower life expect...

Background: The role of the church in addressing healthcare disparities, particularly human immunodeficiency virus (HIV) and/or acquired immunodeficiency syndrome (AIDS), and how pastors’ attitudes influence the devel...

IntroductionHIV testing is central to early diagnosis and HIV prevention, yet uptake among youth remains suboptimal in many low- and middle-income countries. Our study examined HIV testing uptake and its associated facto...

Abstract Introduction In Tanzania, despite the progress in HIV testing and counseling, 39.4% of people living with HIV aged ≥ 15 years were unaware of their HIV status in 2017. HIV testing is a crucial entry point ...

Abstract Background Mozambique bears a high HIV burden, with low testing uptake among young women. This study analyzes socio-demographic and behavioral factors influencing HIV testing among women aged 15–49, using data...

Abstract Background Despite the expansion of antiretroviral treatment programmes, the incidence and mortality of HIV-associated cryptococcal meningitis remain high in Africa. Cryptococcal antigen (CrAg) in the blood prec...

Abstract Background Despite low human immunodeficiency virus (HIV) prevalence in The Gambia (estimated adult prevalence 1.29% in 2024), the country faces a substantial burden, with approximately 25,000 people living with...

Abstract Background Despite antiretroviral therapy (ART), people with HIV (PWH) face immunological ageing and accelerated comorbidities including coronary artery disease (CAD). Gut mucosal damage, chronic inflammation, a...