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Conventional approaches for the detection of antibody dependent cell-mediated cytotoxicity (ADCC) activity rely on quantification of the release of traceable compounds from target cells or flow cytometry analysis of popu...

Orbital imaging has undergone a significant transformation over the past few decades, evolving from basic radiographic techniques to sophisticated cross-sectional imaging modalities. Historically, conventional radiograph...

Abstract Background Proximal humerus fractures are common injuries in the elderly, frequently treated with plate osteosynthesis. Intraoperative 2D fluoroscopy provides only limited visualization of the humeral head’s c...

Abstract Background Gastric cancer (GC) remains a major global health challenge with persistently poor survival rates, largely attributable to late-stage diagnosis and the inherent limitations of conventional imaging mod...

When a surface plasmon propagates along a microrough grating, it interacts with the periodic plus the random roughness and emits light into the diffuse background, which can present intensity maxima called diffuse light ...

Abstract Background Capsule endoscopy offers a new method for visualization of the gastrointestinal mucosa in horses where other imaging technologies have diagnostic limitations. Objectives To (1) test the feasibility of...

Background and aimsChronic appendicitis complicated with diarrhea presents diagnostic and therapeutic challenges due to its atypical and prolonged symptoms, often mimicking functional gastrointestinal disorders. This stu...

Reporter genes are employed to improve visualization of specific tissues by creating a higher contrast in MR imaging. The genes on the magnetosome gene island (MAI) in magnetotactic bacteria have been of interest as cont...

Background Heaves is a severe debilitating condition of horses, characterized by lower airway inflammation and permanent structural changes of the bronchial wall. Chronic inflammation promotes the formation of new vessel...

ABSTRACT High‐resolution fluorescence microscopy deep inside thick, live specimens remains a major challenge due to scattering and limited penetration depth. Structured illumination microscopy (SIM) is widely used for ...

Abstract Background Knee osteoarthritis (OA) is a leading global cause of disability, yet conventional tools lack sensitivity for early detection and precise prognostication. Artificial intelligence (AI) and machine lear...

Abstract This work investigates the impact of a generalized quadratic-cubic form of self-phase modulation together with nonlinear chromatic dispersion on perturbed quiescent optical solitons governed by the Fokas–Lenel...

Abstract Reliable interpretation of clinical imaging requires integrating complementary evidence across modalities, yet most AI systems remain limited by single-modality analysis and poor generalization across institutio...

Cholangiocarcinoma (CCA), a life-threatening malignancy with a poor prognosis, remains diagnostically challenging due to the limited sensitivity and specificity of traditional imaging in differentiating malignant from be...

Abstract Background The insular cortex (IC), a pivotal hub for pain signal integration, projects extensively to the thalamus. However, the functional role of its specific projection to the central medial thalamic nucleus...

Nanophotonic light–matter interfaces hold great promise for quantum technologies. Enhancing local electromagnetic fields, they enable highly efficient detectors, can help realize optically connected processors, or serv...

Abstract Neoadjuvant chemotherapy (NAC) induces critical morphological and vascular changes in breast cancer tumors, yet existing deep learning techniques in medical imaging tend to neglect these longitudinal changes thr...

Although photothermal therapy (PTT) has demonstrated its clinical value and adaptability, it still requires imaging guidance to motivate the development of precise and effective treatment. For PTT, high-resolution visual...

Abstract Molecular-genetic imaging has greatly advanced clinical diagnosis and prognosis monitoring. However, the specific visualization of intracellular proteins such as estrogen receptor (ER) and progesterone receptor ...

BackgroundRadical prostatectomy remains a key curative treatment for localized prostate cancer which has undergone continuous transformation. Recent developments in robot-assisted and single-port surgery have followed th...

Abstract Objectives To evaluate the clinical utility of “multi-echo recombined gradient echo” (MERGE)-based bone-like MRI for delineating acetabular osseous morphology in developmental dysplasia of the hip (DDH), and...

This study presents a comprehensive approach to nail condition classification using multi-illumination imaging and uncertainty-aware deep learning. We developed a diagnostic system capturing nail images under ten lightin...

Background: Small-bore needle arthroscopy (SNA) has emerged as a minimally invasive diagnostic tool in outpatient orthopaedics, allowing direct intra-articular visualization and serving as a potential alternative to magn...