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Background: Mycoplasma and Ureaplasma species are understudied opportunistic pathogens that infect humans, animals and plants. These infections are often asymptomatic, which, together with fastidious growth requireme...

BackgroundVancomycin-resistant Enterococcus faecium (VR-Efm) has shown a rising global trend. This study aimed to analyze the resistance patterns and risk factors of E. faecium bloodstream infections (BSIs) in hospitaliz...

Abstract Introduction Bone and joint infections (BJIs) are complex and difficult to eradicate, and have high relapse rates and limited oral treatment options. Tetracyclines combine favorable bone penetration, oral bioava...

Background: Sexually transmitted infections (STIs) remain a significant public health challenge in Malawi, affecting millions of people every year. Despite the availability of effective treatments, STIs can have a signi...

Abstract Introduction Respiratory syncytial virus (RSV) is the leading cause of respiratory infections and hospitalization among infants and a major burden on pediatric emergency department (EDs). Nirsevimab has recently...

Abstract Background Surgical site infections (SSIs) continue to exert a substantial burden on healthcare systems, particularly in resource-limited settings where they contribute to prolonged hospitalizations, escalated c...

Aims: Acute hand and wrist infections can be devastating, with a substantial burden in low- and middle-income countries (LMICs) compared with high-income countries. Access to treatment, particularly surgery, can be limit...

ABSTRACT Background and Aim Blood transfusion is a vital and life‐saving procedure, saving millions of lives across the world every year. However, it also presents a significant risk of spreading transfusion‐transmis...

ObjectiveMulti-drug resistant (MDR) bacterial infections have become a pressing global health issue due to increasing antibiotic resistance in clinical settings. This study aimed to identify and analyze the patterns of M...

Abstract Background Infection is a significant complication of diabetes, yet comprehensive assessments of risk factors for infections in individuals with diabetes are scarce. We aimed to identify risk factor profiles and...

The diversity of Sarcocystis spp. infecting Alaskan marine mammals is largely unknown, which is relevant in a region of the world where hunting and consumption of marine mammals is essential to Alaskan native food securi...

Background. Respiratory infections remain a major global health burden with significant economic impact. The di-versity of viral pathogens and variability in diagnostic approaches complicate etiological verification in l...

BackgroundCatastrophic antiphospholipid syndrome (CAPS) is a rare and life-threatening manifestation of antiphospholipid syndrome (APS), which is frequently later diagnosed with high mortality.Case reportA 54-year-old wo...

IntroductionChronic granulomatous disease (CGD) is an inborn error in immunity that results in increased infectious susceptibility to serious infections, often from catalase-positive organisms, due to defects in the NADP...

Introduction: Infections caused by vector-borne pathogens and zoonotic agents are a great economic burden in developing countries like India because their numbers keep increasing every year. National programs like the Na...

BackgroundSolid organ transplantation is an effective treatment for end-stage organ diseases, including renal, hepatic, cardiac, and pulmonary failure (1). Long-term graft survival depends on sustained immunosuppression;...

Abstract Background Patients with AIDS Suffering from sepsis secondary to pulmonary infections admitted to intensive care units (ICUs) carry a high burden of morbidity and mortality. Therefore, rapid identification and t...

IntroductionIncreased risk of infections in patients with hematological malignancies (HM) is a growing concern. Immunoglobulin-replacement therapy (IgRT) is used to reduce infection risk in patients who develop secondary...

Abstract Background There is a demand for broad-spectrum products effective against internal and external parasites to simplify dog-owner compliance with veterinary parasiticide treatment recommendations. A field study i...

CARMIL2 is a protein required for T cell activation, specifically for CD28 and CARMA-1/PKC coupling and NF-kB signaling. CARMIL2 deficiency has pleiotropic presentations, which can include recurrent viral and mucocutaneo...

Background Dermatologic infections complicated by sepsis represent a significant yet understudied cause of mortality in the United States, with evolving epidemiological patterns that warrant investigation. Objective To e...

Abstract Background Hepatitis C virus (HCV) remains a global public health concern. Despite the availability of direct-acting antivirals (DAAs), many infections remain undiagnosed—particularly in older adults excluded ...

Abstract Toxoplasma gondii, Plasmodium spp., and Leishmania spp. collectively infect billions and cause millions of deaths worldwide. In French Guiana, the geographical coexistence of malaria, acute toxoplasmosis, and cu...

BackgroundBloodstream infections (BSI) are life-threatening conditions initiated by pathogens entering the circulation, with Staphylococcus aureus among the most lethal causative agents. The liver is the primary site for...