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OBJECTIVE: Atherosclerotic vascular disease (AVD) is the most frequent complication seen in hemodialysis (HD) patients. Evidence suggests that inflammation may play a role in the pathogenesis and progression of atheroscl...

Airborne particulate matter 10 (PM10) induces lung inflammation. However, interventions remain limited. We evaluated the protective effects of Chrysanthemum zawadskii var. latilobum (CZL) against PM10-induced lung injury...

IntroductionIndividuals with obesity may be at a higher risk of developing severe periodontitis. We previously reported that C-C motif ligand 19 (CCL19) plays a pivotal role in adipose inflammation in obesity and that ad...

Ureteral calculi are common in urological practice, and ureteroscopic holmium laser lithotripsy (HLUL) is the preferred minimally invasive treatment. However, postoperative residual fragments and inflammatory responses r...

ABSTRACT Background and Objectives Systemic inflammation indices derived from complete blood counts (CBC) are accessible markers of inflammatory burden, but their relationship with circulating cytokines in psoriasis rema...

Huangtao Ruan,1,2,* Xiaozhao Lu,2,3,* Huan Lu,2– 4,* Haozhang Huang,2,3,* Zuxian Huang,1,2 Shangyi Tang,2,3 Ziyao Yuan,2,5 Rengui Jiang,2,3,6 Jiazhen Xin,6 Tao Tang,6 Jin Liu,1,2 Yong Li...

Abstract Background and aim Severe pneumonia is associated with high mortality rates. Nutritional and inflammatory status significantly impacts outcomes. While albumin-based indices have been demonstrated to predict outc...

Abstract Objective To investigate the association between the Systemic Immune-Inflammation Index (SII), Systemic Inflammation Response Index (SIRI), and in-stent restenosis (ISR) following percutaneous coronary intervent...

BackgroundThe systemic immune-inflammation index (SII) has emerged as a widely studied inflammatory biomarker reflecting the balance between host inflammatory and immune status, although evidence in lung cancer patients ...

ObjectiveSystemic inflammatory response plays a key role in the pathogenesis of endometriosis. This study aimed to investigate the association between the aggregate index of systemic inflammation (AISI), defined as neutr...

BackgroundChronic obstructive pulmonary disease (COPD) continues to pose a significant global burden, which may be exacerbated by pro-inflammatory diets. This study aimed to investigate the association between the Dietar...

ObjectiveSarcopenia is a progressive and complex disorder associated with higher morbidity and mortality, which significantly increases the financial burden and medical costs. This study aims to investigate the relations...

Prenatal exposure to fine particulate matter (PM2.5) has been associated to childhood atopic dermatitis (AD), but the critical exposure window and the role of maternal inflammatory pathways remain unclear. We analyzed 40...

ABSTRACT Background and Aims Chronic inflammation contributes to various chronic diseases, emphasizing the need for reliable biomarkers for early detection and understanding its causes. Measuring chronic inflammation pos...

Abstract Background Systemic inflammation and nutritional status are increasingly recognized as prognostic determinants in glioblastoma (GBM). The CRP–albumin–lymphocyte (CALLY) index integrates inflammatory and immu...

Inflammation-related diseases, including cardiovascular diseases, immune disorders, and infectious diseases, have high prevalence and disability rates, imposing heavy socioeconomic and healthcare burdens. Thus, elucidati...

BackgroundSevere fungal pneumonia with sepsis carries high mortality. Early and accurate prognosis is essential for improving outcomes. We developed and validated a nomogram based on immune-inflammation-nutrition indicat...

Polycystic ovary syndrome (PCOS) is a common endocrine disorder in reproductive-age women, characterized by hormonal, metabolic, and inflammatory changes. Chronic low-grade inflammation plays a key role in its pathogenes...

Introduction. Necrobiosis lipoidica (NL) is a granulomatous skin disease of still only partially known pathogenesis. Microangiopathy is considered as one of the most important processes in NL, and vascular endothelial ...

Abstract Background This study was motivated by the high prevalence of anemia of inflammation (AI) in systemic lupus erythematosus (SLE) and the poorly explored potential link between the underlying inflammatory drive an...

ABSTRACT Epoxyeicosatrienoic acids (EETs) have shown preventive effects against various metabolic diseases. The objective of this study was to investigate the effects and mechanisms of EETs onT2DM in rats. The rats were ...

Background and objectiveEndothelial dysfunction is a key driver of cardiovascular complications in individuals with impaired glucose tolerance (IGT), with oxidative stress and inflammation playing pivotal roles in its pa...

Abstract In bronchial asthma, M2 macrophage polarization and PI3K/Akt/mTOR pathway activation are critically implicated in airway inflammation and remodeling. This study employed an OVA-induced asthmatic mouse model to e...

IntroductionWe have previously demonstrated that intratracheal lipopolysaccharide (LPS) injection induces significant pulmonary inflammation accompanied by hippocampal microglial activation, indicative of neuroinflammati...