Buscar recursos académicos

Background: The growth of a topical vehicle microemulsions has been more enhanced compared to the normal skin applications such as creams, gels among others. These micro-structured vehicles showed enhanced solubilization...

Cayenne pepper contains capsaicin, which exhibits properties that promote hair growth. Microemulsion is an oil and water dispersion system with a particle size of 10-200 nm which can be used topically as a drug delivery ...

Se realiza un estudio de biodisponibilidad relativa de dos formas farmacéuticas de fenitoína, según un diseño aleatorio, cruzado y compensado, en 8 voluntarios sanos, tomando comprimidos comercializados en plaza como...

The objective of the present investigation was to develop and evaluate microemulsion-based hydrogel (MBH) for the topical delivery of sinomenium. The solubility of sinomenium in oils and surfactants was evaluated to iden...

Las microemulsiones son mezclas isotrópicas, estables, claras, constituidas por una fase oleosa, una acuosa y uno o más anfifílicos. Despiertan interés a nivel farmacéutico debido a varias ventajas que ofrecen: ca...

Atualmente, muito se tem discutido nos campos farmacêutico e dermocosmético sobre os riscos da exposição exagerada às radiações UVA e UVB. Neste contexto, a fotoproteção assume papel fundamental na manutenção ...

The aim of the present study was to prepare, characterize and in-vitro evaluation of a Winsor-IV type microemulsion based drug delivery system incorporating celecoxib as BCS class-II model drug. Attempts were made to pre...

IntroductionChlamydia trachomatis (Ct) is the most common bacterial cause of sexually transmitted infection worldwide. Given the limited effectiveness of current Ct screening and treatment programs, alongside the lack of...

We present a study of the microscopic dynamics of water trapped in reverse non-ionic micelles by means of a series of molecular dynamics simulations. The analysis of the effects of micellar confinement on spectroscopical...

Various specially designed poly(acrylamide-co-N-isopropylacrylamide) (PAA-NIPA) nanoparticles (NPs) with different acrylamide (AA)/NIPA molar compositions were synthesized by microemulsion polymerization and evaluated as...

The crystal form of semiconductor materials is keenly correlated with the photosensitivity of optoelectronic devices. Thus, understanding the crystal form-dependent photosensitivity mechanism is critical. In this work, t...

A new microemulsion formula (Sandimmun Neoral: SIM-NO) was developed to solve the problem of variable absorption and lower bioavailability of conventional Sandimmune (SIM), showed 74 to 139% better bioavailability, and w...

Hydroquinone (HQ) is a drug reported to possess manifold biological activities. HQ is highly unstable into various topical vehicles, presenting low topical bioavailability and a relevant level of toxicity. The Pluronic®...

Lipid-based nanocarriers were prepared by hot solvent diffusion technique. Tristearin (TS) and/or castor oil were employed as oily phase, and Lutrol F68® or Solutol HS15® and lecithin were employed as surfactant and co...

A self-emulsifying drug delivery system (SEDDS) of a poorly water soluble drug, irbesartan (IRB), was designed. The aim was to improve the solubility as well as dissolution rates of IRB. Solubility of IRB in different ...