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This study employs molecular dynamics (MD) simulations to systematically investigate the effects of the degree of polymerization (DP 10, 20, and 35) on the mechanical and tribological properties of nitrile butadiene rubb...

Abstract Background Gastric cancer (GC) remains a major global health challenge with persistently poor survival rates, largely attributable to late-stage diagnosis and the inherent limitations of conventional imaging mod...

Abstract Objective By using molecular network technology to analyze the transmission characteristics of the CRF55_01B strain in Yunnan Province, we aimed to identify high-risk transmitters, trace the origin time, locatio...

Red blood cells (RBCs), formerly viewed as mere oxygen transporters, are now acknowledged as dynamic biological entities with intricate molecular characteristics which impact their deformability, lifespan, and interactio...

Background: Scoring of tumor infiltrating lymphocytes (TIL’s) in breast carcinoma specimens has gained increasing value as it has prognostic and predictive value in certain molecular subtypes of breast cancer especiall...

Cystic hydatid disease, caused by Echinococcus granulosus, is a major zoonotic infection with significant public health and economic impact in endemic regions, including Iraq. This study aimed to detect the mitochondrial...

A molecularly imprinted solid-phase extraction (MISPE) sorbent has been developed for the separation of RIV from serum sample. Molecularly imprinted polymer (MIP) was prepared via non-covalent imprinting technique using ...

ABSTRACT Antiferroelectrics (AFEs) with typical reversible electrically antipolar‐polar phase transformation have attracted tremendous attention for assembling electronic devices. As a thriving part of the family, mole...

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cholinergic dysfunction, making acetylcholinesterase (AChE) a key therapeutic target. Although Garcinia kola has been widely reported ...

Yuan Cui,1,2 Jingyi Hu,1 Yanan Li,1 Yiheng Tong,1 Hong Shen1 1Department of Gastroenterology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210001,...

Abstract Eleusine coracana (L.) Gaertn., commonly known as Ragi or finger millet, is a nutrient-rich cereal traditionally valued for its health-promoting properties. However, its precise molecular mechanisms and therapeu...

Observations of molecular structures on scales of ∼0.1−50 pc show that the specific angular momentum ( j ) scales with radius ( R ) as j  ∼  R ^3/2 . We study the effects of turbulence, gravity, and the magnetic ...

The functions of the intestinal system are crucial for animal health and productivity, as they ensure digestion, nutrient absorption, immune homeostasis, and microbiota regulation. Molecular markers of the intestinal sys...

BackgroundGranular cell astrocytoma (GCA) is a rare, morphologically distinct variant of IDH-wildtype glioblastoma that can appear deceptively low-grade yet behave aggressively. Its molecular features remain poorly defin...

Abstract Polygonati Rhizoma has been reported to exhibit the ability to retard skin aging. However, the precise molecular mechanisms underlying remain largely elusive. In this study, we screened 9 active compounds in Pol...

Benzo[a]pyrene (BaP), a widespread environmental pollutant, has been increasingly implicated in the pathogenesis of chronic degenerative diseases. Environmental pollutants have recently been recognized as emerging risk f...

Background: Barrett's esophagus (BE) represents a critical precancerous lesion arising from chronic gastroesophageal reflux disease (GERD), with significant risk of progression to esophageal adenocarcinoma. Despite advan...

Abstract The pre-training molecular representation learning (MRL) has shown considerable potential in computer-aided drug discovery. Recently, many multimodal pre-training MRL methods have been presented, incorporating m...

Abstract Industrialization and urbanization exacerbate global environmental health challenges, with pollutants from industrial and vehicular emissions (e.g., PAHs, NOx, PM2.5) posing significant risks. Growing evidence l...

Traditional rice varieties are known to exhibit anti-oxidant, anti-inflammatory, anti-diabetic, anti-cancer, and cardioprotective properties due to their nutritional profile and diverse phytochemical composition. The pre...

IntroductionLung adenocarcinoma remains the most common subtype of non–small cell lung cancer (NSCLC), yet molecular epidemiology and real-world outcomes in Caribbean populations are poorly documented.MethodsWe conduct...

Abstract The role of Bisphenol A (BPA) in endometrial cancer (EC) remains uncertain. In this study, we integrated toxicological prediction, network toxicology, gene expression profiling, survival analysis, and molecular ...

Type 2 diabetes mellitus (T2DM) is characterized by chronic metabolic dysfunction and low-grade inflammation. This study aimed to identify inflammation-associated molecular targets in T2DM and to computationally evaluate...

Lignin, the most abundant aromatic polymer from nature, represents a promising feedstock for sustainable functional materials. Yet its intrinsic structural heterogeneity and broad molecular weight distribution limit its ...