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46 resultados encontrados.

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Molecular Analysis and Activities of Bioactive Compounds from Symbiont Bacteria Isolates Polycarpa aurata
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Molecular Analysis and Activities of Bioactive Compounds from Symbiont Bacteria Isolates Polycarpa aurata
Herwin Herwin et al · Universitas Gadjah Mada · 2026 · ISSN 1410-5918
Symbiont bacteria associated with Polycarpa aurata are known to produce secondary metabolites with diverse bioactive properties, including antibacterial, anticancer, antifungal, and antiprotozoal activities. This study e...
LCC LCC:MedicineIdioma eng
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Molecular analysis of somatic mutations at the HPRT locus in lymphocytes of human population exposed to chronic high background natural radiation
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Molecular analysis of somatic mutations at the HPRT locus in lymphocytes of human population exposed to chronic high background natural radiation
Anila Gopinathan et al · Nature Portfolio · 2026 · ISSN 2045-2322
Abstract Populations residing in high-level natural radiation areas (HLNRA) along the monazite-rich coastal belt of Kerala, India, are chronically exposed to low-dose ionizing radiation, with lifetime cumulative doses ex...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Comparative molecular analysis of colorectal cancer in Saudi Arabia: distinct genetic alterations and clinical features
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Comparative molecular analysis of colorectal cancer in Saudi Arabia: distinct genetic alterations and clinical features
Maha-Hamadien Abdulla et al · Frontiers Media S.A · 2026 · ISSN 2234-943X
PurposeGlobally, colorectal cancer (CRC) stands as the third most common type of cancer, a ranking that has remained consistent over recent years. However, the scenario diverges in Saudi Arabia, where CRC ascends to the ...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Molecular Detection and Genetic Diversity of Measles and Parainfluenza Viruses Circulating in Humans in Bangladesh: A Cross‐Sectional Study
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Molecular Detection and Genetic Diversity of Measles and Parainfluenza Viruses Circulating in Humans in Bangladesh: A Cross‐Sectional Study
Shusmita Dutta Choudhury et al · Wiley · 2026 · ISSN 2398-8835
ABSTRACT Background and Aims Among Paramyxoviruses (PMVs), measles virus (MeV) and human parainfluenza virus (HPIV) are major contributors to respiratory tract infections worldwide. Despite recurrent outbreaks of MeV and...
LCC LCC:MedicineIdioma eng
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Molecular dynamics simulation investigation into the effects of polymerization degree on the tribological properties of NBR
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Molecular dynamics simulation investigation into the effects of polymerization degree on the tribological properties of NBR
Li Zeyun et al · De Gruyter · 2026 · ISSN 1618-7229
This study employs molecular dynamics (MD) simulations to systematically investigate the effects of the degree of polymerization (DP 10, 20, and 35) on the mechanical and tribological properties of nitrile butadiene rubb...
LCC LCC:Polymers and polymer manufactureIdioma eng
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Molecular network characteristics and transmissible drug resistance of HIV-1 CRF55_01B in Yunnan Province
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Molecular network characteristics and transmissible drug resistance of HIV-1 CRF55_01B in Yunnan Province
Yuan Li et al · BMC · 2026 · ISSN 1471-2334
Abstract Objective By using molecular network technology to analyze the transmission characteristics of the CRF55_01B strain in Yunnan Province, we aimed to identify high-risk transmitters, trace the origin time, locatio...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Aspergillus flavus glutathione transferase as a potential approach for synthesis of epothilone-glutathione conjugates with enhanced anticancer activity for the drug-resistant cells: characterization and molecular docking analysis
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Aspergillus flavus glutathione transferase as a potential approach for synthesis of epothilone-glutathione conjugates with enhanced anticancer activity for the drug-resistant cells: characterization and molecular docking analysis
Ashraf S. A. El-Sayed et al · BMC · 2026 · ISSN 1471-2180
Abstract Epothilone is one of the lead anticancer compounds, with unique binding affinity to the cellular β-tubulin, however, the solubility and efficiency towards the drug-resistant tumors are the challenges. Glutathio...
LCC TENDOk1pY3JvYmlvbG9neQ~~Idioma eng
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Network pharmacology, pathway enrichment, and molecular docking analysis reveal the multi target therapeutic potential of phytochemicals from Eleusine coracana
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Network pharmacology, pathway enrichment, and molecular docking analysis reveal the multi target therapeutic potential of phytochemicals from Eleusine coracana
Amisha Bisht et al · Springer · 2026 · ISSN 3005-1193
Abstract Eleusine coracana (L.) Gaertn., commonly known as Ragi or finger millet, is a nutrient-rich cereal traditionally valued for its health-promoting properties. However, its precise molecular mechanisms and therapeu...
LCC TENDOkNoZW1pc3RyeQ~~Idioma eng
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Integrated computational analysis of Garcinia kola phytochemicals as acetylcholinesterase inhibitors: molecular docking, molecular dynamics simulations, and DFT studies
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Integrated computational analysis of Garcinia kola phytochemicals as acetylcholinesterase inhibitors: molecular docking, molecular dynamics simulations, and DFT studies
Onyekachi Onyekwere et al · Elsevier · 2026 · ISSN 3050-7871
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cholinergic dysfunction, making acetylcholinesterase (AChE) a key therapeutic target. Although Garcinia kola has been widely reported ...
LCC TENDOkNvbXB1dGVyIGFwcGxpY2F0aW9ucyB0byBtZWRpY2luZS4gTWVkaWNhbCBpbmZvcm1hdGljcw~~Idioma eng
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Phytochemical-mediated green synthesis of selenium nanoparticles using Catharanthus roseus and their physicochemical characterization, biological evaluation, and molecular docking analysis
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Phytochemical-mediated green synthesis of selenium nanoparticles using Catharanthus roseus and their physicochemical characterization, biological evaluation, and molecular docking analysis
Abeer F. Desouky et al · Nature Portfolio · 2026 · ISSN 2045-2322
Abstract This study reports the green biosynthesis of bioactive selenium nanoparticles using Catharanthus roseus extract as a reducing and stabilizing agent. Liquid chromatography–electrospray ionization tandem mass sp...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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The effect of organic acids mixture in the form of glycerids on the regulation of intestinal barrier function in piglets using SCFA-M: analysis of molecular markers
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The effect of organic acids mixture in the form of glycerids on the regulation of intestinal barrier function in piglets using SCFA-M: analysis of molecular markers
Andrii Gavrylenko et al · Institute of Animal Biology NAAS · 2026 · ISSN 1681-0015
The functions of the intestinal system are crucial for animal health and productivity, as they ensure digestion, nutrient absorption, immune homeostasis, and microbiota regulation. Molecular markers of the intestinal sys...
LCC LCC:Biology (General); TENDOlZldGVyaW5hcnkgbWVkaWNpbmU~Idioma eng
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Foundational Analysis of the Impact of Mechanical Stress on Molecular Size Distribution in Immune Globulin Intravenous, Human-stwk, 10%
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Foundational Analysis of the Impact of Mechanical Stress on Molecular Size Distribution in Immune Globulin Intravenous, Human-stwk, 10%
Stacey Ness et al · Rockefeller University Press · 2026 · ISSN 3065-8993
IntroductionIt is imperative to minimize protein aggregates in commercial intravenous immunoglobulin (IVIG) therapy as they have been implicated in adverse events and can enhance immunogenicity for patients receiving IVI...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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Hedyotis diffusa and Scutellaria barbata enhance the anti-ovarian cancer effect of cisplatin through network pharmacology analysis and molecular docking technology
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Hedyotis diffusa and Scutellaria barbata enhance the anti-ovarian cancer effect of cisplatin through network pharmacology analysis and molecular docking technology
Ran Bi et al · Nature Portfolio · 2026 · ISSN 2045-2322
Abstract Hedyotis diffusa Willd (HD) and Scutellaria barbata D.Don (SB) are widely used traditional Chinese herbs with detoxifying properties and anti-tumor activities. The HD-SB pairing demonstrated significant anti-tum...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Integrated analysis of Morusin inhibiting esophageal cancer via network pharmacology molecular dynamics simulation and in vitro validation
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Integrated analysis of Morusin inhibiting esophageal cancer via network pharmacology molecular dynamics simulation and in vitro validation
Miyuan Yang et al · Springer · 2026 · ISSN 2730-6011
Abstract Esophageal cancer (EC) is a malignant tumor characterized by high incidence and mortality, and its complex pathogenesis necessitates the development of effective therapeutic strategies. In this study, we investi...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Integrative machine learning analysis suggests novel molecular targets for liver cancer diagnosis and therapy
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Integrative machine learning analysis suggests novel molecular targets for liver cancer diagnosis and therapy
Fengrui Zhou et al · Springer · 2026 · ISSN 2730-6011
Abstract Background Hepatocellular carcinoma (HCC) is a critical condition characterized by unchecked cellular growth in the liver, often leading to systemic inflammation and organ failure. Although its complex molecular...
LCC TENDOk5lb3BsYXNtcy4gVHVtb3JzLiBPbmNvbG9neS4gSW5jbHVkaW5nIGNhbmNlciBhbmQgY2FyY2lub2dlbnM~Idioma eng
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Characterisation and molecular detection of Echinococcus granulosus in Duhok Governorate
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Characterisation and molecular detection of Echinococcus granulosus in Duhok Governorate
HUSSEIN L. H. et al · Sciendo · 2026 · ISSN 1336-9083
Cystic hydatid disease, caused by Echinococcus granulosus, is a major zoonotic infection with significant public health and economic impact in endemic regions, including Iraq. This study aimed to detect the mitochondrial...
LCC TENDOk1pY3JvYmlvbG9neQ~~Idioma eng
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Bioinformatics analysis implicates ferroptosis and key hub genes in the pathogenesis of endometriosis
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Bioinformatics analysis implicates ferroptosis and key hub genes in the pathogenesis of endometriosis
Jia-yan Xu et al · Taylor & Francis Group · 2026 · ISSN 0144-3615
Objective Endometriosis (EMs) is a chronic gynaecological condition characterised by the ectopic growth of endometrial tissue; however, its molecular mechanisms remain insufficiently understood. Ferroptosis, an iron-depe...
LCC TENDOkd5bmVjb2xvZ3kgYW5kIG9ic3RldHJpY3M~Idioma eng
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Efficacy and safety evaluation of thromboprophylaxis strategies for central venous catheter-related thrombosis in cancer patients: a bayesian network meta-analysis and bibliometric analysis
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Efficacy and safety evaluation of thromboprophylaxis strategies for central venous catheter-related thrombosis in cancer patients: a bayesian network meta-analysis and bibliometric analysis
Mingyu Meng et al · Frontiers Media S.A · 2026 · ISSN 1663-9812
BackgroundCatheter-related thrombosis (CRT) is a common complication following central venous catheter (CVC) placement in patients with cancer, increasing mortality and adverse outcomes. However, robust evidence on optim...
LCC LCC:Therapeutics. PharmacologyIdioma eng
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Genome-wide identification of the CmHDZ gene family in Chinese chestnut (Castanea mollissima) and analysis of their expression patterns under different types of abiotic stress
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Genome-wide identification of the CmHDZ gene family in Chinese chestnut (Castanea mollissima) and analysis of their expression patterns under different types of abiotic stress
Xiurong Xu et al · Frontiers Media S.A · 2026 · ISSN 1664-462X
The members of the homologous homeodomain-leucine zipper (HDZ) family of transcription factors play important roles in the ability of plants to cope with adverse conditions. In this study, we analyzed the genome of the C...
LCC TENDOlBsYW50IGN1bHR1cmU~Idioma eng
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Network Pharmacology, Molecular Docking and Dynamics Simulation Reveal the Anti-Colitis Mechanism of Smilax glabra Roxb.
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Network Pharmacology, Molecular Docking and Dynamics Simulation Reveal the Anti-Colitis Mechanism of Smilax glabra Roxb.
Cui Y et al · Dove Medical Press · 2026 · ISSN 1178-7023
Yuan Cui,1,2 Jingyi Hu,1 Yanan Li,1 Yiheng Tong,1 Hong Shen1 1Department of Gastroenterology, Jiangsu Province Hospital of Chinese Medicine, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, 210001,...
LCC LCC:Diseases of the digestive system. GastroenterologyIdioma eng
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The regulatory mechanism of NLRP3 inflammasome in the “immune paralytic-overactivation” imbalance in sepsis: the latest progress from molecular signaling to clinical translation
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The regulatory mechanism of NLRP3 inflammasome in the “immune paralytic-overactivation” imbalance in sepsis: the latest progress from molecular signaling to clinical translation
Gaosheng Zhou et al · Frontiers Media S.A · 2026 · ISSN 1664-3224
Sepsis remains a major challenge in critical care medicine worldwide, characterized by a dynamic imbalance of the immune system between two extremes: “immunoparalysis” and “hyperactivation.” This dysregulation se...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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A regulatory network underlying glume hardness revealed by transcriptomic analysis of an ems-induced mutant in synthetic hexaploid wheat
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A regulatory network underlying glume hardness revealed by transcriptomic analysis of an ems-induced mutant in synthetic hexaploid wheat
Xin Liu et al · BMC · 2026 · ISSN 1471-2164
Abstract Background Tenacious glume a key trait limiting threshing efficiency in synthetic hexaploid wheat (SHW), represents an ancestral defense mechanism inherited from wild progenitors. Despite its evolutionary import...
LCC TENDOkJpb3RlY2hub2xvZ3k~; LCC:GeneticsIdioma eng
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Exploring the roles of Polygonati Rhizoma in delaying skin aging using network pharmacology and molecular docking
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Exploring the roles of Polygonati Rhizoma in delaying skin aging using network pharmacology and molecular docking
Xilong Wang et al · Nature Portfolio · 2026 · ISSN 2045-2322
Abstract Polygonati Rhizoma has been reported to exhibit the ability to retard skin aging. However, the precise molecular mechanisms underlying remain largely elusive. In this study, we screened 9 active compounds in Pol...
LCC LCC:Medicine; TENDOlNjaWVuY2U~Idioma eng
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Integrating network toxicology and experimental validation to elucidate the molecular mechanism basis of chondrotoxicity of Benzo[a]pyrene in osteoarthritis
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Integrating network toxicology and experimental validation to elucidate the molecular mechanism basis of chondrotoxicity of Benzo[a]pyrene in osteoarthritis
Jingxin Pan et al · Elsevier · 2026 · ISSN 0147-6513
Benzo[a]pyrene (BaP), a widespread environmental pollutant, has been increasingly implicated in the pathogenesis of chronic degenerative diseases. Environmental pollutants have recently been recognized as emerging risk f...
LCC LCC:Environmental pollution; TENDOkVudmlyb25tZW50YWwgc2NpZW5jZXM~Idioma eng
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