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Intrauterine growth restriction is described as a fetus not reaching its growth potential during pregnancy. Placental malperfusion is the main cause of Intrauterine growth restriction . Management of Intrauterine Gowth ...

Abstract High-throughput omics technologies have transformed our understanding of female reproductive biology, revealing molecular interactions governing oocyte maturation, ovarian reserve, endometrial receptivity, and e...

BackgroundApproximately 40-60% of patients with locally advanced esophageal squamous cell carcinoma (ESCC) exhibit suboptimal responses to neoadjuvant chemoimmunotherapy (NCIT), highlighting the need for predictive bioma...

Abstract Objectives IgG4-related disease (IgG4-RD) is an immune-mediated condition with diagnostic challenges in clinical practice. Sensitive biomarkers are needed for diagnosis, disease activity and disease progression ...

ABSTRACT Background and Aims Sepsis remains a leading cause of morbidity and mortality worldwide, particularly in low‐ and middle‐income countries where diagnostic delays are common. The complete blood count (CBC) is...

Post-transplant lymphoproliferative disorders (PTLD) represent a heterogeneous group of complications with rising complexity, particularly as EBV-negative forms are increasingly recognized in adult recipients. While earl...

Background Lupus nephritis (LN) is a leading cause of mortality in patients with systemic lupus erythematosus (SLE), and the accurate classification of renal pathological subtypes is crucial for reducing mortality rates ...

tWe carried out a caging field experiment to assess the potential effects of an untreated sewage effluenton the health status of Prochilodus lineatus. We analyzed multiple biomarker responses, which includedmorphological...

Abstract Background Circulating creatinine and symmetric dimethylarginine (SDMA) are biomarkers of kidney function that have been used variously to define stable vs progressive chronic kidney disease (CKD). Slope monitor...

Emmanuel Ifeanyi Obeagu1– 3 1Division of Haematology, Department of Biomedical and Laboratory Science, Africa University Mutare, Mutare, Zimbabwe; 2Department of Molecular Medicine and Haematology, School of Pathology,...

IntroductionSchnitzler syndrome (SchS) is a rare, late-onset, acquired autoinflammatory disorder characterized by recurrent urticarial lesions, monoclonal gammopathy and systemic inflammation. Although interleukin-1 (IL-...

Erythrocyte nuclear abnormalities (ENA) serve as sensitive biomarkers of genotoxic and physiological stress in fish. However, little is known about the extent to which age influences the frequency of ENA in species with ...

Background and Aim: Objective assessment of the postoperative acute phase response following major orthopedic surgery, such as tibial plateau leveling osteotomy (TPLO), is essential for distinguishing uncomplicated recov...

Abstract Background Anti-amyloid monoclonal antibodies are entering clinical practice for early symptomatic Alzheimer’s disease (AD), but European real-world data on feasibility, safety, and biomarker monitoring remain...

IntroductionEarly identification of adolescents at risk for substance use is critical for timely intervention. However, standard screening tools like CRAFFT (Car, Relax, Alone, Forget, Family and Friends, Trouble) and S2...

Immune checkpoint inhibitors (ICIs) have been game changer in cancer therapy but can trigger diverse immune-related adverse events (irAEs) that impact multiple organs. This review offers a unified perspective on irAE ris...

ABSTRACT Background and Aims Myocardial injury after non‐cardiac surgery (MINS) is a significant postoperative complication. In 2022, the European Society of Cardiology (ESC) updated its guidelines, recommending periop...

Abstract Background Understanding how the respiratory microbiota matures with age is key to improving poultry health and pathogen surveillance, yet the ecological processes shaping this transition remain elusive. We aime...

As a Class I human carcinogen ubiquitous in both industrial and household environments, benzene can cause hematopoietic damage even at low concentrations. However, its precise hematological toxicological molecular mechan...

Abstract Parkinson’s Disease (PD) is a progressive neurodegenerative disorder that causes motor and cognitive impairments, affecting approximately 1% of individuals over 60 years of age. Speech impairments are among th...

ABSTRACT Background and Aims Heparin‐binding protein (HBP) has the potential clinical utility in the early diagnosis and prognosis evaluation of infectious diseases. We aimed to assess the early diagnostic value of HBP...

Background: Conventional electrocardiography (ECG) analysis faces a persistent dichotomy: Expert-defined features provide interpretability but are limited in capturing latent high-dimensional patterns, whereas deep learn...

The aim of the present work was to study the effect of the pyrethroid cypermethrin (CYP) on the non-target freshwater snail Chilina parchappi. Initially, the sensitivity of adult snails to CYP was evaluated via the 96-h ...

Abstract Type 1 diabetes (T1D) is an autoimmune disease characterized by β-cell destruction and insulin deficiency. Circulating microRNAs (miRNAs) are promising biomarkers for disease monitoring and complication risk as...