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Objective: To develop an artificial intelligence (AI) driven plan tradeoff decision making assistant for radiation oncologists. Methods: A user interface (UI) was developed to integrate the assistant with the treatment p...

BackgroundSolid pseudopapillary tumors (SPTs) of the pancreas are rare, low-grade malignancies that generally have favorable outcomes when diagnosed at an early stage and can be resected. However, treatment options for p...

Acute pancreatitis (AP) urgently requires new therapeutic strategies. Here, we developed a maltose-alginate synbiotic microcapsule (AM-AR113) for intestinal delivery of Lactiplantibacillus plantarum AR113 and evaluated i...

Objective: In contrast to penetrating trauma, blunt pancreatic trauma poses numerous challenges for treating surgeons, mainly due to the different clinical manifestations. Materials and methods: This is a retrospective o...

The peroxisome proliferator-activated receptors (PPARs), including PPAR-α, PPAR-β/δ, and PPAR-γ, are nuclear receptors that play critical roles in regulating metabolism and inflammation. While PPARs have been extensi...

Diabetes mellitus (DM) is a disease characterized by hyperglycemia and impaired glucose, protein, and fat metabolism due to insulin deficiency or resistance. In type 2 DM, insulin resistance potentially causes dyslipidem...

BackgroundWestern diet (WD) consumption accelerates the development of metabolic syndrome (MetS) and type 2 diabetes mellitus (T2DM). This study investigated whether chestnut-derived ellagitannins (FT50) modulate early m...

ABSTRACT This study aimed to evaluate the development of the gastrointestinal tract and organs in 18-days embryos (ED18) and newly hatched chicks from broiler breeders supplemented with conjugated linoleic acid (CLA), as...

Abstract Purpose Intraoperative radiotherapy (IORT) is designed to deliver a precise dose of ionizing radiation to a tumor or tumor bed after surgical resection. The IORT procedure can deliver targeted radiation to the t...

ObjectivePancreatic disorders are characterised by high mortality rates and limited therapeutic options and pose a global health challenge. As a dual-function organ with endocrine and exocrine roles, the pancreas exhibit...

Resumen: Las mutaciones germinales en genes de predisposición al cáncer han dejado de ser una información sólo asociada al riesgo de cáncer hereditario, en la actualidad se han convertido en un verdadero motor de ca...

The two principal cell types of the exocrine pancreas, acinar and ductal cells, serve distinct but complementary roles. Acinar cells synthesize and secrete digestive enzymes, whereas duct cells secrete fluid and bicarbon...

Abstract Purpose Differential diagnoses of primary pancreatic lesions include pancreatic ductal adenocarcinomas (PDAC) and inflammatory lesions of the pancreas (ILP). Post-pancreatic surgery, differentiation of postopera...

Abstract Background Small cell carcinoma is a highly aggressive neuroendocrine malignancy that most commonly arises in the lungs, gastrointestinal tract, or pancreas. Primary small cell neuroendocrine carcinoma of the en...

Abstract IgG4-related disease (IgG4-RD) is a systemic inflammatory condition marked by tissue infiltration of IgG4-positive plasma cells, often resulting in fibrosis. While IgG4-RD commonly affects organs such as the pan...

Introdução: Os tumores neuroendócrinos pancreáticos (pNET) originam-se das células endócrinas das Ilhotas de Langerhans no pâncreas. Trata-se de neoplasias de comportamento clínico heterogêneo e prognóstico var...