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IntroductionAntimicrobial resistance (AMR) is rising globally, particularly among the clinically important ESKAPE pathogens, a group of bacteria responsible for a large number of hospital-acquired infections and known fo...

Background. Viral infections remain a major global health threat despite advances in vaccines and antiviral drugs due to the rapid emergence of resistance and new viral pathogens. Antiviral peptides (AVPs) are promising ...

Because of resistance development by cancer cells against current anticancer drugs, there is a considerable interest in developing novel antitumor agents. We have previously demonstrated that CIGB-552, a novel cell-penet...

Amyloids constitute a class of protein and protein fragments believed to be involved in the pathologies associated with Alzheimer’s, Parkinson’s and Creutzfeldt‐ Jakob diseases. These proteins can self‐assemble i...

Abstract Background The most investigated form of autoimmune-long-QT-syndrome (LQTS) is caused by circulating anti-Ro/SSA(Sjögren’s syndrome-related antigen-A)-52kD antibodies, which cross-react with a specific sequen...

Abstract The in-situ upcycling of decentralized methane and nitrogen gas (N2)-derived ammonia via methanotrophic bacteria is highly attractive. However, the toxic intermediate generated from ammonia oxidation significant...

Jiahui Zhang,1– 3,* Junran Tong,1– 3,* Yang Sun,4,* Jinpeng Sun,1– 3 Ran Gao,1– 3 Di Sun,5 Xiaopeng Guo,6 Yumiao Wei1– 3 1Department of Cardiology, Union Hospital, Tongji Medical College...

Abstract Background Gastric cancer (GC) remains a major global health challenge with persistently poor survival rates, largely attributable to late-stage diagnosis and the inherent limitations of conventional imaging mod...

Biologic therapeutics have transformed the treatment of chronic and life-threatening diseases, yet their clinical use depends almost entirely on parenteral administration. Oral delivery is the preferred route for patient...

A method development aimed for high-throughput and automated antibody screening holds great potential for areas ranging from fundamental molecular interactions to the discovery of novel disease markers, therapeutic targe...

We used dynamic mechanical analysis (DMA) to evaluate soy flour adhesives made with and without a conventional crosslinking agent, polyamideamine-epichlorohydrin (PAE). Fixed-frequency and constant strain rate studies re...

Materias / palabras clave: amino acid metabolism, protein synthesis, peptide engineering, therapeutic applications, biotechnological applications, nutritional aspects; Science: Chemistry: Organic chemistry: Biochemistry; Science: Biology (General)