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A classification model based on G protein-coupled estrogen receptor binding affinity: development and validation

ISSN: 10048456 · Editor / fuente: The Editorial Office of Chinese Journal of Food Hygiene

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Protein structure and selection pressure in plants: using mutation to understand the functional importance of protein structure
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Protein structure and selection pressure in plants: using mutation to understand the functional importance of protein structure
Evan Long et al · BMC · 2026 · ISSN 1471-2164
Abstract Recent advances in protein structure prediction have opened new avenues for understanding the potential impact of genetic mutations and how they might affect protein structure. In this study, we analyzed the dis...
LCC TENDOkJpb3RlY2hub2xvZ3k~; LCC:GeneticsIdioma eng
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Protein-protein interactions are a major source of epistasis in genetic interaction networks
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Protein-protein interactions are a major source of epistasis in genetic interaction networks
Xavier Castellanos-Girouard et al · Nature Portfolio · 2026 · ISSN 2041-1723
Abstract Genetic interaction and protein-protein interaction networks have proved among the most important tools for inference of gene function and genotype-phenotype relationship. It remains unclear, however, how these ...
LCC TENDOlNjaWVuY2U~Idioma eng
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Assessment value of blood pressure variability combined with serum tau protein for the prognosis of patients with traumatic brain injury
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Assessment value of blood pressure variability combined with serum tau protein for the prognosis of patients with traumatic brain injury
Feng Lin et al · Frontiers Media S.A · 2026 · ISSN 1664-2295
ObjectiveTo investigate the prognostic value of blood pressure variability (BPV) combined with serum tau protein in patients with traumatic brain injury (TBI).MethodsA total of 205 TBI patients were prospectively enrolle...
LCC LCC:Neurology. Diseases of the nervous systemIdioma eng
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Clinical significance of renal histological diagnosis in patients with type 2 diabetes and proteinuria atypical for diabetic nephropathy
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Clinical significance of renal histological diagnosis in patients with type 2 diabetes and proteinuria atypical for diabetic nephropathy
Shogo Kuwagata et al · Wiley · 2026 · ISSN 2040-1116
ABSTRACT Background/Aim Most patients with proteinuria are considered to have typical diabetic nephropathy (DN). However, when proteinuria occurs without diabetic retinopathy, with hematuria, or persists despite strict g...
LCC LCC:Diseases of the endocrine glands. Clinical endocrinologyIdioma eng
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DSS-PPI: a self-supervised graph learning framework for protein-protein interaction prediction via multimodal sequence semantics
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DSS-PPI: a self-supervised graph learning framework for protein-protein interaction prediction via multimodal sequence semantics
Shumei Li et al · BMC · 2026 · ISSN 1471-2164
Abstract Background Reliable identification of protein‑protein interactions (PPIs) is crucial for deciphering cellular functional networks. Current research models still face limitations in aligning heterogeneous featu...
LCC TENDOkJpb3RlY2hub2xvZ3k~; LCC:GeneticsIdioma eng
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Dietary protein intake, inflammatory biomarkers, genetic susceptibility, and the incidence of sarcopenia: a prospective population-based study
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Dietary protein intake, inflammatory biomarkers, genetic susceptibility, and the incidence of sarcopenia: a prospective population-based study
Hongxia Xia et al · Frontiers Media S.A · 2026 · ISSN 2296-861X
BackgroundSarcopenia elevates risks of falls, hospitalization, and mortality in older adults. Despite protein’s importance for muscle maintenance, evidence on its overall and source-specific role in sarcopenia developm...
LCC LCC:Nutrition. Foods and food supplyIdioma eng
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Evaluating network-based algorithms for protein function prediction using plant protein-protein interaction networks
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Evaluating network-based algorithms for protein function prediction using plant protein-protein interaction networks
M. A.S.U. Piyatissa et al · BMC · 2026 · ISSN 1471-2229
Abstract Background Protein-protein interaction (PPI) network-based protein function prediction algorithms, which use the guilt-by-association principle, are widely applied in medical and human domains, but they are comp...
LCC TENDOkJvdGFueQ~~Idioma eng
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Intraspecific geographical variability of Phlebotomus perniciosus assessed by MALDI-TOF MS protein profiling
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Intraspecific geographical variability of Phlebotomus perniciosus assessed by MALDI-TOF MS protein profiling
Vit Dvorak et al · BMC · 2026 · ISSN 1756-3305
Abstract Background Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) protein profiling has emerged over the last decade as a method of choice for species identification of many ...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Egyptian river buffalo (Bubalus bubalis) mitogenome sequence: characterization and analysis of variations in protein- and transfer RNA-coding genes
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Egyptian river buffalo (Bubalus bubalis) mitogenome sequence: characterization and analysis of variations in protein- and transfer RNA-coding genes
Amal A. M. Hassan et al · SpringerOpen · 2026 · ISSN 2090-990X
Abstract Background Genetic analysis of the mitochondrial genome (mitogenome) has become essential for breed characterization, population genetics, and taxonomic studies in livestock. Genetic variations in mitochondrial ...
LCC TENDOlpvb2xvZ3k~Idioma eng
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Pyruvate metabolism enzyme Dlat induces mitochondria protein hyperacetylation to limit fatty acid oxidation in the HFpEF heart
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Pyruvate metabolism enzyme Dlat induces mitochondria protein hyperacetylation to limit fatty acid oxidation in the HFpEF heart
Ying Wang et al · Nature Portfolio · 2026 · ISSN 2041-1723
Abstract Increased protein acetylation is frequently observed in the failing heart, including in hearts with heart failure with preserved ejection fraction (HFpEF). However, its role in the pathogenesis of HFpEF remains ...
LCC TENDOlNjaWVuY2U~Idioma eng
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Searching for α−solenoid proteins involved in organellar gene expression
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Searching for α−solenoid proteins involved in organellar gene expression
Céline Cattelin et al · BMC · 2026 · ISSN 1471-2164
Abstract Background In photosynthetic eukaryotes of the green lineage, the expression of the chloroplast genome is mainly regulated post-transcriptionally, by RNA-binding proteins encoded in the nuclear genome termed org...
LCC TENDOkJpb3RlY2hub2xvZ3k~; LCC:GeneticsIdioma eng
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Comparative transcriptome analysis reveals stress-response pathways as key drivers of nitrogen use efficiency in tobacco under low-nitrogen conditions
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Comparative transcriptome analysis reveals stress-response pathways as key drivers of nitrogen use efficiency in tobacco under low-nitrogen conditions
Shichen Li et al · BMC · 2026 · ISSN 1471-2229
Abstract Background Enhancing nitrogen use efficiency (NUE) is essential for sustainable agriculture. Stress response pathways play a significant role in regulating NUE across various growth stages and organs. Therefore,...
LCC TENDOkJvdGFueQ~~Idioma eng
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Kidney dysfunction and its associated factors among people living with HIV on antiretroviral therapy in rural Rwanda: a cross-sectional study
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Kidney dysfunction and its associated factors among people living with HIV on antiretroviral therapy in rural Rwanda: a cross-sectional study
Jean Baptiste Niyibizi et al · BMC · 2026 · ISSN 1471-2334
Abstract Background People living with HIV (PLHIV) have a higher risk of developing stage 3–5 of Chronic Kidney Disease (CKD) and this risk is further impacted by the use of antiretrovirals including Tenofovir disoprox...
LCC TENDOkluZmVjdGlvdXMgYW5kIHBhcmFzaXRpYyBkaXNlYXNlcw~~Idioma eng
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Making sense of invisible densities in single-particle cryo-EM
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Making sense of invisible densities in single-particle cryo-EM
Xiaoxuan Lin et al · International Union of Crystallography · 2026 · ISSN 2052-2525
In the era of single-particle cryogenic electron microscopy (cryo-EM) and AI-driven protein structure prediction, obtaining high-resolution protein structures, either experimentally or computationally, has become increas...
LCC TENDOkNyeXN0YWxsb2dyYXBoeQ~~Idioma eng
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Piperlonguminine inhibits hen egg white lysozyme amyloid fibril formation and mitigates amyloid fibril–induced hepatocellular damage
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Piperlonguminine inhibits hen egg white lysozyme amyloid fibril formation and mitigates amyloid fibril–induced hepatocellular damage
Gangqiang Liu et al · Elsevier · 2026 · ISSN 2665-9271
Protein misfolding and aggregation into amyloid fibrils (AFs) are critical issues associated with protein stability during food processing and storage, as well as with pathological damage in organisms. Hen egg white lyso...
LCC LCC:Nutrition. Foods and food supply; TENDOkZvb2QgcHJvY2Vzc2luZyBhbmQgbWFudWZhY3R1cmU~Idioma eng
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Luteolin induces mitochondria-dependent apoptosis and senescence in myelodysplastic syndrome cells by targeting the Akt signaling pathway
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Luteolin induces mitochondria-dependent apoptosis and senescence in myelodysplastic syndrome cells by targeting the Akt signaling pathway
LI Jiarun et al · Editorial Office of Journal of Army Medical University · 2026 · ISSN 2097-0927
Abstract Objective Myelodysplastic syndromes (MDS) are associated with a high risk of progression to leukemia, highlighting the critical need to explore novel therapeutic agents. Based on network pharmacology predicti...
LCC TENDOk1lZGljaW5lIChHZW5lcmFsKQ~~Idioma zho
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Novel Pathogenic Variant in IL2RG Affecting the Signal Peptide Results in mRNA Instability, Decreased IL2RG Expression, and Atypical Late-Onset Immunodeficiency
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Novel Pathogenic Variant in IL2RG Affecting the Signal Peptide Results in mRNA Instability, Decreased IL2RG Expression, and Atypical Late-Onset Immunodeficiency
Muslima Hussain et al · Rockefeller University Press · 2026 · ISSN 3065-8993
X-linked severe combined immunodeficiency (SCID-X1) presents as T-B+NK- SCID, due to mutations in the common γ chain (IL2RG/CD132), a shared component of several cytokine receptors. Without definitive therapy, SCID-X1 i...
LCC LCC:Immunologic diseases. AllergyIdioma eng
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