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Abstract Introduction Respiratory syncytial virus (RSV) poses a significant health risk to older adults, particularly those with chronic comorbidities, in the Gulf Cooperation Council (GCC) countries. Despite its high bu...

Abstract Background Inspiratory muscle training combined with positive expiratory pressure (IMT/PEP) may improve outcomes in chronic obstructive pulmonary disease (COPD), but evidence in exacerbation‑prone (Group E) di...

Background and purpose: Mediastinal lymphoma patients are typically young and are at risk of long-term radiation-induced adverse events, making organ of interest (OOI) sparing a key objective of radiotherapy. This study ...

Background and purpose: Proton therapy is a promising modality for treating locally advanced non-small cell lung cancer (LA-NSCLC). However, respiratory-induced intra-fractional motion can compromise tumour coverage. Thi...

Abstract Introduction Older adults (OAs) and individuals with underlying comorbidities are at increased risk for severe respiratory syncytial virus (RSV) disease (e.g., lower respiratory tract disease [LRTD]) and related...

Abstract Introduction Respiratory syncytial virus (RSV) is a major cause of morbidity and mortality among older adults. Limited information is available in Israel regarding RSV outcomes, particularly compared to influenz...

Abstract Introduction Respiratory syncytial virus (RSV) is the leading cause of respiratory infections and hospitalization among infants and a major burden on pediatric emergency department (EDs). Nirsevimab has recently...

Abstract Effective respiratory therapy relies heavily on inhaler device efficiency and patient technique. While device performance is well-documented in idealized induction ports, there remains a critical lack of data in...

BackgroundAlthough drug rash with eosinophilia and systemic symptoms (DRESS) and anticonvulsant hypersensitivity syndrome are well-known complications of anti-seizure medications (ASMs), lesser-known immunologic complica...

BackgroundPulsed dye laser (PDL) therapy is the gold standard for treating port-wine stains (PWS) in children but frequently requires procedural analgosedation due to pain and the need for immobility. The optimal sedativ...

BackgroundN-acetylcysteine (NAC) is a key precursor of glutathione (GSH), the lung’s principal antioxidant. First developed as a mucolytic, NAC is now recognized for broader antioxidant, anti-inflammatory, immunomodula...

ASCENIV is a 10% intravenous immune globulin (IVIG) indicated for the treatment of primary humoral immunodeficiency (PI) in adults and adolescents (12 to 17 years of age). ASCENIV contains a blend of normal source plasma...

Background and Literature ReviewHypereosinophilic syndrome (HES) is a rare, heterogeneous group of disorders defined by persistent hypereosinophilia (>1,500 cells/µL) with eosinophil-mediated end-organ damage. Its estim...

Abstract Background Lower respiratory tract infection (LRTI) is a leading cause of hospitalization and antibacterial use globally. In low- and middle-income countries (LMICs), limited diagnostic resources contribute to i...

Chunyan Lin, Ting Huang, Huangyi Wu, Yanzhu Lin, Chunling Guo, Liduan Li NICU, the Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, 362000, People’s Republic of ChinaCorrespondence: Liduan Li,...

Background: Diaphragm excursion is a prevalent condition often overlooked in relation to postpartum low back pain. Diaphragmatic function plays a vital but often underrecognized role in postpartum low back pain (LBP). Th...

Abstract Introduction Omadacycline is indicated for the treatment of acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia. With limited real-world data, we report the clinical exp...

Abstract Asthma is a chronic inflammatory airway disease with a rising global prevalence and impact on quality of life. Conventional therapeutics such as corticosteroids and β2-agonists are associated with various long-...

Massive pulmonary embolism (PE) is uncommon but potentially fatal, requiring immediate thrombolytic therapy. Thrombolysis, however, carries a significant bleeding risk and is generally contraindicated in cases of active ...

100 million adults and 15 million adolescents currently use e-cigarettes, a type of Electronic Nicotine Delivery System (ENDS) or Electronic Non-Nicotine Delivery System (ENNDS). While they were introduced as smoking ces...

ABSTRACT Aims This study aimed to assess the nutritional status of COVID‐19 patients within the first 24 h of Intensive Care Unit (ICU) admission and to determine its association with the risk of mechanical ventilati...

IntroductionKabuki syndrome (KS) is a rare, complex, multisystem, neurodevelopmental congenital disorder with characteristic phenotypic anomalies and pathogenic genetic variants of the KMT2D or KDM6A genes. KS is highly ...

The nuclear factor kappa light-chain enhancer of activated B cells (NFKB1) pathway is a central regulator of inflammatory gene expression. NFKB1 haploinsufficiency can present with common variable immunodeficiency (CVID)...