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As the prevalence of chronic rhinosinusitis (CRS) and allergic rhinitis (AR) continues to rise worldwide, more and more patients are reporting a lower quality of life. In addition to causing common nasal symptoms such as...

BackgroundAllergic rhinitis (AR) involves Th2/Th17 immune dysregulation and nasal epithelial barrier dysfunction; however, the molecular mechanisms linking these processes remain unclear.ObjectiveHere, we investigated wh...

Abstract Background Endoscopic vidian neurectomy has been performed for decades on patients with refractory allergic rhinitis and vasomotor rhinitis. Although the surgical approach has evolved continuously, it still has ...

IntroductionRNU4ATAC-opathies are characterized by biallelic pathogenic variants and include three recognized phenotypes: autosomal recessive Roifman syndrome, microcephalic osteodysplastic primordial dwarfism (MOPD), an...

IntroductionSporotrichosis is an uncommon but emerging opportunistic infection in immunocompromised patients. Primary pulmonary sporotrichosis can disseminate and result in significant morbidity and mortality, despite tr...

Allergic rhinitis (AR), asthma, and their combined allergic rhinitis and asthma syndrome (CARAS) frequently coexist. However, the underlying pathophysiological and metabolic mechanisms, as well as reliable diagnostic dif...

Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is a monogenic disorder caused by loss-of-function mutations in the FOXP3 gene, which is critical for the development of functional regulato...

Abstract This study aimed to investigate the effects of air pollution and urbanization on the rate of allergic rhinitis and COPD in Turkey. Allergy and COPD rates compiled from the Turkish Ministry of Health Statistical ...

Background22q11.2 deletion syndrome (DS) is the most common chromosomal microdeletion syndrome and a leading cause of developmental delay, congenital heart disease, and varying degrees of T cell immunodeficiency. While m...

Introduction: In recent years, the prevalence of atopic diseases among children has increased. Increasing evidence suggests that early gut microbiota development, shaped in part by the mode of delivery, feeding practices...

BackgroundAllergic conjunctivitis (AC) frequently coexists with allergic rhinitis (AR), together known as allergic rhinoconjunctivitis (ARC), but ocular symptoms are often underemphasized in efficacy assessments using co...