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An explainable multi-head attention network for healthcare IoT threat detection based on the MedDefender-MHAN framework.

Ali Alqazzaz · Public Library of Science (PLoS) · 2026

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The rapid proliferation of Internet of Medical Things (IoMT) devices in healthcare environments has created critical cybersecurity vulnerabilities that demand both accurate and interpretable intrusion detection solutions. Existing deep learning-based intrusion detection systems (IDS) achieve high detection accuracy but lack inherent explainability, limiting their clinical adoption under regulatory frameworks such as GDPR and FDA guidelines. This paper presents MedDefender-MHAN, an explainable multi-head attention network specifically designed for healthcare IoT threat detection. The proposed framework introduces a novel dual-stream architecture that combines convolutional neural networks for local spatial feature extraction with transformer-based encoders for long-range temporal dependency modeling. Unlike existing approaches that apply explainability as a post-hoc process, MedDefender-MHAN embeds interpretability directly into the multi-head attention mechanism, enabling real-time gradient-weighted explanation generation without external XAI pipelines. Evaluated on CICIDS2017 and TON_IoT benchmark datasets, MedDefender-MHAN achieves detection accuracies of 99.47% and 98.92% respectively, with sub-3ms inference latency and a throughput of 435 samples per second. Explainability evaluation demonstrates 94.6% alignment with expert-annotated attack signatures and 91.9% temporal accuracy, outperforming post-hoc methods such as SHAP and Integrated Gradients. These results confirm that MedDefender-MHAN provides a clinically viable, regulatory-compliant security solution for real-world healthcare IoT infrastructure. The proposed framework addresses the dual imperatives of methodological transparency and clinical impact, directly responding to the growing need for trustworthy AI-driven security solutions in regulated healthcare IoMT environments.

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APA 7

Alqazzaz, A. (2026). An explainable multi-head attention network for healthcare IoT threat detection based on the MedDefender-MHAN framework. https://doi.org/10.1371/journal.pone.0346677

MLA

Alqazzaz, Ali. "An explainable multi-head attention network for healthcare IoT threat detection based on the MedDefender-MHAN framework." 2026. https://doi.org/10.1371/journal.pone.0346677.

Chicago

Alqazzaz, Ali. 2026. "An explainable multi-head attention network for healthcare IoT threat detection based on the MedDefender-MHAN framework.". https://doi.org/10.1371/journal.pone.0346677.

Harvard

Alqazzaz, A. 2026, An explainable multi-head attention network for healthcare IoT threat detection based on the MedDefender-MHAN framework, Public Library of Science (PLoS), available at: https://doi.org/10.1371/journal.pone.0346677 [Accessed 7 Aug. 2026].

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Title
An explainable multi-head attention network for healthcare IoT threat detection based on the MedDefender-MHAN framework.
Author / contributors
Ali Alqazzaz
Publisher
Public Library of Science (PLoS)
Publication year
2026
ISSN
1932-6203
ISSN
1932-6203
Language
English
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