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Preparation and characterization of pH sensitive hydrogel for sustained release of metoclopramide

Humaira Sultana et al · AMMANIF · 2023

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Author / responsible party
Humaira Sultana et al
Publisher
AMMANIF
Year
2023
ISSN
2521-0521
ISSN
2521-0521
Language
English

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Summary

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Objective: The aim of present research work was focus on preparation of PVA/SA hydrogels for Metoclopramide HCl drug release and investigates swelling and release study. Method: Chemical cross-linking method was used for the preparation of PVA/SA hydrogels in which glutaraldehyde was used as cross linker. By changing the concentration of polymers and cross linker different samples were prepared. Results: Characterization was done by FTIR, Sol gel analysis, swelling studies. Release studied was carried out at in pH (1.2-7.5) of phosphate buffer and its absorbance was determined by using UV spectrophotometer. Zero order, 1st order, Higuchi and Korsmeyer- Peppas model were used to evaluate the drug release. Conclusion: It was concluded from the study that hydrogel could be one of the best approaches to enhanced sustained release of metoclopramide.

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APA 7

al, H. S. E. (2023). Preparation and characterization of pH sensitive hydrogel for sustained release of metoclopramide. https://nodovox.com/record.php?id=307640

MLA

al, Humaira Sultana et. "Preparation and characterization of pH sensitive hydrogel for sustained release of metoclopramide." 2023. https://nodovox.com/record.php?id=307640.

Chicago

al, Humaira Sultana et. 2023. "Preparation and characterization of pH sensitive hydrogel for sustained release of metoclopramide.". https://nodovox.com/record.php?id=307640.

Harvard

al, H. S. E. 2023, Preparation and characterization of pH sensitive hydrogel for sustained release of metoclopramide, AMMANIF, available at: https://nodovox.com/record.php?id=307640 [Accessed 9 Aug. 2026].

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Title
Preparation and characterization of pH sensitive hydrogel for sustained release of metoclopramide
Author / contributors
Humaira Sultana et al
Publisher
AMMANIF
Publication year
2023
ISSN
2521-0521
ISSN
2521-0521
Language
English

Subjects

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Hydrogels; Cross-linking; Sodium alginate; Polyvinyl alcohol; FTIR
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