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The Pfam Protein Families Database

Alex Bateman · Nucleic Acids Research · 2002

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Pfam is a large collection of protein multiple sequence alignments and profile hidden Markov models. Pfam is available on the World Wide Web in the UK at http://www.sanger.ac.uk/Software/Pfam/, in Sweden at http://www.cgb.ki.se/Pfam/, in France at http://pfam.jouy.inra.fr/ and in the US at http://pfam.wustl.edu/. The latest version (6.6) of Pfam contains 3071 families, which match 69% of proteins in SWISS-PROT 39 and TrEMBL 14. Structural data, where available, have been utilised to ensure that Pfam families correspond with structural domains, and to improve domain-based annotation. Predictions of non-domain regions are now also included. In addition to secondary structure, Pfam multiple sequence alignments now contain active site residue mark-up. New search tools, including taxonomy search and domain query, greatly add to the functionality and usability of the Pfam resource.

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APA 7

Bateman, A. (2002). The Pfam Protein Families Database. https://doi.org/10.1093/nar/30.1.276

MLA

Bateman, Alex. "The Pfam Protein Families Database." 2002. https://doi.org/10.1093/nar/30.1.276.

Chicago

Bateman, Alex. 2002. "The Pfam Protein Families Database.". https://doi.org/10.1093/nar/30.1.276.

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Bateman, A. 2002, The Pfam Protein Families Database, Nucleic Acids Research, available at: https://doi.org/10.1093/nar/30.1.276 [Accessed 6 Aug. 2026].

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Title
The Pfam Protein Families Database
Author / contributors
Alex Bateman
Publisher
Nucleic Acids Research
Publication year
2002
Language
English

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