Optical Coherence Tomography

David Huang; Eric A. Swanson; Charles P. Lin; Joel S. Schuman; William G. Stinson; Warren Chang; Michael R. Hee; Thomas Flotte · Science · 1991

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Author / responsible party

David Huang; Eric A. Swanson; Charles P. Lin; Joel S. Schuman; William G. Stinson; Warren Chang; Michael R. Hee; Thomas Flotte

Publisher

Science

Year

1991

Language

English

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A technique called optical coherence tomography (OCT) has been developed for noninvasive cross-sectional imaging in biological systems. OCT uses low-coherence interferometry to produce a two-dimensional image of optical scattering from internal tissue microstructures in a way that is analogous to ultrasonic pulse-echo imaging. OCT has longitudinal and lateral spatial resolutions of a few micrometers and can detect reflected signals as small as approximately 10(-10) of the incident optical power. Tomographic imaging is demonstrated in vitro in the peripapillary area of the retina and in the coronary artery, two clinically relevant examples that are representative of transparent and turbid media, respectively.

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APA 7

Huang, D, Swanson, E. A, Lin, C. P, Schuman, J. S, Stinson, W. G, Chang, W, Hee, M. R, & Flotte, T. (1991). Optical Coherence Tomography. https://doi.org/10.1126/science.1957169

MLA

Huang, David, et al. "Optical Coherence Tomography." 1991. https://doi.org/10.1126/science.1957169.

Chicago

Huang, David, Eric A. Swanson, Charles P. Lin, Joel S. Schuman, William G. Stinson, Warren Chang, Michael R. Hee, and Thomas Flotte. 1991. "Optical Coherence Tomography.". https://doi.org/10.1126/science.1957169.

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Huang, D. et al. 1991, Optical Coherence Tomography, Science, available at: https://doi.org/10.1126/science.1957169 [Accessed 8 Aug. 2026].

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Resource details

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Title: Optical Coherence Tomography

Author / contributors: David Huang; Eric A. Swanson; Charles P. Lin; Joel S. Schuman; William G. Stinson; Warren Chang; Michael R. Hee; Thomas Flotte

Publisher: Science

Publication year: 1991

Language: English

Subjects

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Optical coherence tomography; Optics; Interferometry; Tomography; Coherence (philosophical gambling strategy); Tomographic reconstruction; Materials science; Biomedical engineering; Physics; Medicine; Quantum mechanics