News Help Institutional access
Back to results
Bibliographic record · Consultation and access
Artículo de revista

From Tumor Marker to Congestion Indicator: The Expanding Role of CA‐125 in Heart Failure and Beyond

Minoo Heidari Almasi et al · Wiley · 2026

Open access available
Quick overview. Review the resource’s basic details, then access the content using the main button. This page shows only the information needed to identify, cite, and open the work.
Author / responsible party
Minoo Heidari Almasi et al
Publisher
Wiley
Year
2026
ISSN
2398-8835
ISSN
2398-8835
Language
English
Serial publication

A Comparative Study on Hypochondriasis Among Medical and Dental Students in Post‐COVID‐19 Pandemic: A Cross‐Sectional Study

This serial publication contains 222 related contents.
View contents

Resource access

Open the content from the main option or choose another available source.

DOAJ DOAJ Articles
Entrar por DOAJ
Main access

Open access available

Recurso identificado como acceso abierto, sin confirmar automáticamente si es texto completo directo.
Open resource

Summary

Descripción general del contenido del recurso.

ABSTRACT Background and Aims To evaluate the transition of Carbohydrate antigen 125 (CA‐125) from an ovarian tumor marker to a versatile indicator of systemic congestion and fluid overload. Methods A literature review (1984–2025) was conducted using PubMed, Scopus, and Web of Science. Keywords included “CA‐125,” “systemic congestion,” and related terms. Studies on the diagnostic and prognostic value of CA‐125 in congestive disorders were analyzed. Results CA‐125 is synthesized by mesothelial cells in response to mechanical stress and inflammation, particularly via c‐Jun N‐terminal kinase (JNK) signaling pathways. It provides significant prognostic value in heart failure (HF), renal failure, and cirrhosis, often rivaling or complementing NT‐proBNP. Conclusion CA‐125 is a versatile biomarker for systemic congestion, offering diagnostic and prognostic value across cardiology, nephrology, and hepatology. Refining its clinical application could optimize fluid management in diverse patient populations.

How to cite

Elegí el formato que necesitás y copiá la referencia al portapapeles.

APA 7

al, M. H. A. E. (2026). From Tumor Marker to Congestion Indicator: The Expanding Role of CA‐125 in Heart Failure and Beyond. https://doi.org/10.1002/hsr2.71964

MLA

al, Minoo Heidari Almasi et. "From Tumor Marker to Congestion Indicator: The Expanding Role of CA‐125 in Heart Failure and Beyond." 2026. https://doi.org/10.1002/hsr2.71964.

Chicago

al, Minoo Heidari Almasi et. 2026. "From Tumor Marker to Congestion Indicator: The Expanding Role of CA‐125 in Heart Failure and Beyond.". https://doi.org/10.1002/hsr2.71964.

Harvard

al, M. H. A. E. 2026, From Tumor Marker to Congestion Indicator: The Expanding Role of CA‐125 in Heart Failure and Beyond, Wiley, available at: https://doi.org/10.1002/hsr2.71964 [Accessed 9 Aug. 2026].

Share and print

Save the record, copy its permanent link, or print it as a PDF.

Export reference

You can export the record in common formats for use in a reference manager.

RIS BibTeX

Resource details

Bibliographic information to help confirm that this is the correct material.

Title
From Tumor Marker to Congestion Indicator: The Expanding Role of CA‐125 in Heart Failure and Beyond
Author / contributors
Minoo Heidari Almasi et al
Publisher
Wiley
Publication year
2026
ISSN
2398-8835
ISSN
2398-8835
Language
English

Subjects

Explore related resources through these subjects.

biomarker; CA‐125; heart failure; Indicator; oncology
Copied