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Topical Jatropha multifida L. ointment improves perineal wound healing in postpartum mothers: a randomized controlled trial

Fitria Candra Fera et al · Universitas Muhammadiyah Purwokerto · 2026

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Background: Postpartum perineal wound care may lead to infection if not managed properly. Jatropha multifida L. contains various secondary metabolites that may accelerate wound healing; however, clinical evidence remains limited. Objective: This study aimed to evaluate the effectiveness of Jatropha multifida L. extract ointment compared with standard clean and dry wound care in promoting perineal wound healing. Methods: This was a true experimental study with a pre–posttest control group design. A total of 60 postpartum mothers with second-degree perineal lacerations were randomly assigned into three groups: control, 15% extract, and 20% extract. The interventions were applied twice daily for 7 days. Wound healing was assessed on days 3, 5, and 7 using the REEDA (Redness, Edema, Ecchymosis, Discharge, Approximation) score. Results: The Friedman test showed a significant reduction in REEDA scores across all groups (p < 0.001). The greatest decrease was observed in the 15% concentration group (mean = 0.4). Cohen’s d indicated a very large effect size (d = 1.835). Conclusions: Jatropha multifida L. extract ointment at a 15% concentration was effective in improving perineal wound healing in postpartum mothers.

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APA 7

al, F. C. F. E. (2026). Topical Jatropha multifida L. ointment improves perineal wound healing in postpartum mothers: a randomized controlled trial. https://doi.org/10.30595/medisains.v24i1.26811

MLA

al, Fitria Candra Fera et. "Topical Jatropha multifida L. ointment improves perineal wound healing in postpartum mothers: a randomized controlled trial." 2026. https://doi.org/10.30595/medisains.v24i1.26811.

Chicago

al, Fitria Candra Fera et. 2026. "Topical Jatropha multifida L. ointment improves perineal wound healing in postpartum mothers: a randomized controlled trial.". https://doi.org/10.30595/medisains.v24i1.26811.

Harvard

al, F. C. F. E. 2026, Topical Jatropha multifida L. ointment improves perineal wound healing in postpartum mothers: a randomized controlled trial, Universitas Muhammadiyah Purwokerto, available at: https://doi.org/10.30595/medisains.v24i1.26811 [Accessed 8 Aug. 2026].

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Title
Topical Jatropha multifida L. ointment improves perineal wound healing in postpartum mothers: a randomized controlled trial
Author / contributors
Fitria Candra Fera et al
Publisher
Universitas Muhammadiyah Purwokerto
Publication year
2026
ISSN
1693-7309
ISSN
1693-7309
Language
English
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