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Tolerance signaling molecules and pregnancy: IDO, galectins, and the renaissance of regulatory T cells

Terness, Peter et al · Blackwell Munksgaard · 2007

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Author / responsible party
Terness, Peter et al
Publisher
Blackwell Munksgaard
Year
2007
ISSN
1046-7408
ISSN
1046-7408
Language
English

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Is the concept of maternal tolerance preventing rejection of the semi-allogeneic 'fetal allograft' still valid?. Compilation of expert reviews of literature and recent advances in research on indoleamine-2,3 dioxygenase (IDO), regulatory T cells and galectin-1. A role for IDO in pregnancy success remains speculative, but solid data exist to support a role for Treg cells, and for galectin-1 in induction and action of Treg cells. Just as several signals may need to be simultaneously present to induce Th1 cytokine-triggered abortions, more than 1 signal may need to be simultaneously present to prevent rejection and ensure success. Both complement and coagulation pathways appear necessary for embryo execution. Fil: Terness, Peter. Universität Heidelberg; Albania Fil: Kallikourdes, Marinos. MRC Laboratory of Molecular Biology; Reino Unido

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APA 7

Terness, P. E. A. (2007). Tolerance signaling molecules and pregnancy: IDO, galectins, and the renaissance of regulatory T cells. http://hdl.handle.net/11336/27508

MLA

Terness, Peter et al. "Tolerance signaling molecules and pregnancy: IDO, galectins, and the renaissance of regulatory T cells." 2007. http://hdl.handle.net/11336/27508.

Chicago

Terness, Peter et al. 2007. "Tolerance signaling molecules and pregnancy: IDO, galectins, and the renaissance of regulatory T cells.". http://hdl.handle.net/11336/27508.

Harvard

Terness, P. E. A. 2007, Tolerance signaling molecules and pregnancy: IDO, galectins, and the renaissance of regulatory T cells, Blackwell Munksgaard, available at: http://hdl.handle.net/11336/27508 [Accessed 7 Aug. 2026].

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Title
Tolerance signaling molecules and pregnancy: IDO, galectins, and the renaissance of regulatory T cells
Author / contributors
Terness, Peter et al
Publisher
Blackwell Munksgaard
Publication year
2007
ISSN
1046-7408
ISSN
1046-7408
Language
English

Subjects

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Galectin-1; Immune Tolerance; Signal Transduction; Pregnancy; https://purl.org/becyt/ford/3.1; https://purl.org/becyt/ford/3; https://purl.org/becyt/ford/3.1; https://purl.org/becyt/ford/3
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