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Systemic propranolol and topical moist wound dressings for ulcerated infantile hemangioma of the scrotum: a case report

Jiejun Xia et al · Frontiers Media S.A · 2026

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BackgroundUlceration is a common complication of infantile hemangioma, and its management poses unique difficulties when the lesion is located in high-risk areas like the scrotum. This case report details the successful management of this condition using topical moist wound dressings combined with propranolol.Case presentationA 5-month-old male presented with a rapidly progressing, ulcerated scrotal infantile hemangioma characterized by purulent exudate. Systemic treatment involved oral propranolol solution (maintenance dose of 2 mg/kg/d). Local wound care was managed using a tailored moist wound healing strategy: alginate dressing combined with recombinant human epidermal growth factor gel, secured with a transparent film dressing. The patient was treated successfully; localized infection was controlled within 3 days. The wound achieved complete epithelialization after a total of 12 days of consistent combined treatment, accompanied by simultaneous regression of the hemangioma volume. Three-month Follow-up confirmed favorable cosmetic results with no significant hypertrophic scarring.ConclusionThis case underscores that a synergistic regimen of systemic propranolol and a customized moist wound healing strategy can significantly accelerate healing timelines and improve the quality of tissue repair in ulcerated infantile hemangiomas.

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APA 7

al, J. X. E. (2026). Systemic propranolol and topical moist wound dressings for ulcerated infantile hemangioma of the scrotum: a case report. https://doi.org/10.3389/fped.2026.1752616

MLA

al, Jiejun Xia et. "Systemic propranolol and topical moist wound dressings for ulcerated infantile hemangioma of the scrotum: a case report." 2026. https://doi.org/10.3389/fped.2026.1752616.

Chicago

al, Jiejun Xia et. 2026. "Systemic propranolol and topical moist wound dressings for ulcerated infantile hemangioma of the scrotum: a case report.". https://doi.org/10.3389/fped.2026.1752616.

Harvard

al, J. X. E. 2026, Systemic propranolol and topical moist wound dressings for ulcerated infantile hemangioma of the scrotum: a case report, Frontiers Media S.A, available at: https://doi.org/10.3389/fped.2026.1752616 [Accessed 10 Aug. 2026].

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Title
Systemic propranolol and topical moist wound dressings for ulcerated infantile hemangioma of the scrotum: a case report
Author / contributors
Jiejun Xia et al
Publisher
Frontiers Media S.A
Publication year
2026
ISSN
2296-2360
ISSN
2296-2360
Language
English

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