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Internal target volume reproducibility and dose coverage for lung stereotactic body radiotherapy using spine-based positioning and tracking

Thomas Opsommer et al · Elsevier · 2026

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Author / responsible party
Thomas Opsommer et al
Publisher
Elsevier
Year
2026
ISSN
2405-6316
ISSN
2405-6316
Language
English

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Free-breathing spine-based positioning/tracking in lung stereotactic body radiotherapy is required when direct tumor positioning is not possible. Respiratory baseline, motion and target position reproducibility interact and remain uncertainty sources. This results in conflicting margins but also clinical control. The internal target volume geometric reproducibility, spine distance dependency and four-dimensional per-fraction gross tumor volume (GTV) dose was analyzed in 340 fractions. While the target would leave a projected isotropic 5 mm planned target volume in 11% of fractions, ΔD98%(4D-GTV) > 10% occurred in 2.6% of fractions. Risk mitigation is suggested through additional off-line 4DCT, surface guidance, fractionation and increased inferior-superior and posterior-anterior margins.

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APA 7

al, T. O. E. (2026). Internal target volume reproducibility and dose coverage for lung stereotactic body radiotherapy using spine-based positioning and tracking. https://doi.org/10.1016/j.phro.2026.100944

MLA

al, Thomas Opsommer et. "Internal target volume reproducibility and dose coverage for lung stereotactic body radiotherapy using spine-based positioning and tracking." 2026. https://doi.org/10.1016/j.phro.2026.100944.

Chicago

al, Thomas Opsommer et. 2026. "Internal target volume reproducibility and dose coverage for lung stereotactic body radiotherapy using spine-based positioning and tracking.". https://doi.org/10.1016/j.phro.2026.100944.

Harvard

al, T. O. E. 2026, Internal target volume reproducibility and dose coverage for lung stereotactic body radiotherapy using spine-based positioning and tracking, Elsevier, available at: https://doi.org/10.1016/j.phro.2026.100944 [Accessed 8 Aug. 2026].

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Title
Internal target volume reproducibility and dose coverage for lung stereotactic body radiotherapy using spine-based positioning and tracking
Author / contributors
Thomas Opsommer et al
Publisher
Elsevier
Publication year
2026
ISSN
2405-6316
ISSN
2405-6316
Language
English

Subjects

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Internal target volume; Lung tumors; 4D Cone Beam CT; Image-guided Radiotherapy; Stereotactic body radiotherapy
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