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Application of boron-doped diamond modified cobalt oxide nanoparticles (BDD/CoONPs) as an electrochemical sensor for hydrocortisone detection

Yunita Triana et al · Elsevier · 2026

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Author / responsible party
Yunita Triana et al
Publisher
Elsevier
Year
2026
ISSN
1452-3981
ISSN
1452-3981
Language
English

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In this study, a boron-doped diamond (BDD) electrode modified with cobalt oxide nanoparticles (CoONPs) is proposed as a working electrode for hydrocortisone (HC) detection in 0.1 M NaOH. CoONPs were synthesized via a green synthesis approach using Nigella sativa seed extract and cobalt nitrate as precursors. The synthesized CoONPs were characterized in terms of functional groups, elemental composition, and surface morphology. The electrochemical redox behavior of HC was investigated using differential pulse voltammetry (DPV) within a potential range of + 0.5 to + 1.6 V (vs. Ag/AgCl), with variations in pH and analyte concentration to evaluate the sensing performance and determine the limit of detection (LoD). A detection limit of 8.19 × 10⁻³μM was achieved, accompanied by good measurement stability, with repeatability and reproducibility values of 1.43% and 1.03% RSD, respectively. These results demonstrate the strong potential of the BDD/CoONPs electrode for sensitive and reliable HC detection.

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APA 7

al, Y. T. E. (2026). Application of boron-doped diamond modified cobalt oxide nanoparticles (BDD/CoONPs) as an electrochemical sensor for hydrocortisone detection. https://doi.org/10.1016/j.ijoes.2026.101329

MLA

al, Yunita Triana et. "Application of boron-doped diamond modified cobalt oxide nanoparticles (BDD/CoONPs) as an electrochemical sensor for hydrocortisone detection." 2026. https://doi.org/10.1016/j.ijoes.2026.101329.

Chicago

al, Yunita Triana et. 2026. "Application of boron-doped diamond modified cobalt oxide nanoparticles (BDD/CoONPs) as an electrochemical sensor for hydrocortisone detection.". https://doi.org/10.1016/j.ijoes.2026.101329.

Harvard

al, Y. T. E. 2026, Application of boron-doped diamond modified cobalt oxide nanoparticles (BDD/CoONPs) as an electrochemical sensor for hydrocortisone detection, Elsevier, available at: https://doi.org/10.1016/j.ijoes.2026.101329 [Accessed 7 Aug. 2026].

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Title
Application of boron-doped diamond modified cobalt oxide nanoparticles (BDD/CoONPs) as an electrochemical sensor for hydrocortisone detection
Author / contributors
Yunita Triana et al
Publisher
Elsevier
Publication year
2026
ISSN
1452-3981
ISSN
1452-3981
Language
English

Subjects

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BDD; Hydrocortisone; Cobalt; Nanoparticle; Nigella sativa
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