Bacterial Biofilms: A Common Cause of Persistent Infections

J. William Costerton; Philip S. Stewart; E. Peter Greenberg · Science · 1999

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Author / responsible party

J. William Costerton; Philip S. Stewart; E. Peter Greenberg

Publisher

Science

Year

1999

Language

English

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Bacteria that attach to surfaces aggregate in a hydrated polymeric matrix of their own synthesis to form biofilms. Formation of these sessile communities and their inherent resistance to antimicrobial agents are at the root of many persistent and chronic bacterial infections. Studies of biofilms have revealed differentiated, structured groups of cells with community properties. Recent advances in our understanding of the genetic and molecular basis of bacterial community behavior point to therapeutic targets that may provide a means for the control of biofilm infections.

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APA 7

Costerton, J. W, Stewart, P. S, & Greenberg, E. P. (1999). Bacterial Biofilms: A Common Cause of Persistent Infections. Science. https://doi.org/10.1126/science.284.5418.1318

MLA

Costerton, J. William, et al. Bacterial Biofilms: A Common Cause of Persistent Infections. Science, 1999. https://doi.org/10.1126/science.284.5418.1318.

Chicago

Costerton, J. William, Philip S. Stewart, and E. Peter Greenberg. 1999. Bacterial Biofilms: A Common Cause of Persistent Infections. Science. https://doi.org/10.1126/science.284.5418.1318.

Harvard

Costerton, J. W, Stewart, P. S. and Greenberg, E. P. 1999, Bacterial Biofilms: A Common Cause of Persistent Infections, Science, available at: https://doi.org/10.1126/science.284.5418.1318 [Accessed 8 Aug. 2026].

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Resource details

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Title: Bacterial Biofilms: A Common Cause of Persistent Infections

Author / contributors: J. William Costerton; Philip S. Stewart; E. Peter Greenberg

Publisher: Science

Publication year: 1999

Language: English

Subjects

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Biofilm; Microbiology; Bacteria; Antimicrobial; Antibiotic resistance; Biology; Antibiotics; Genetics