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Spectrophotometric Determination of Promethazine in Pharmaceutical Preparations

Sh.H. Mohamad et al · University of Mosul, College of Education for Pure Science · 2006

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Author / responsible party
Sh.H. Mohamad et al
Publisher
University of Mosul, College of Education for Pure Science
Year
2006
ISSN
1812-125X
ISSN
1812-125X
Language
English
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A batch and flow injection (FIA) spectrophotometric methods have been developed for the determination of promethazine in aqueous solution and in pharmaceutical preparations. The methods are based on the reaction of promethazine with sulphanilic acid in the presence of N-bromosuccinimide as oxidizing agent. The water soluble bluish- green dye produced is measured at Xmax 600 nm, linearity is observed from 2-30 and from 2-100 p-gml"1 promethazine with detection limits of 0.20 and 0.43 ^ig ml"1 promethazine by batch and FIA procedures, respectively. The effect of chemical and physical parameters has been carefully considered and the proposed procedures have successfully been applied to the determination of promethazine in pharmaceutical formulations.

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APA 7

al, S. M. E. (2006). Spectrophotometric Determination of Promethazine in Pharmaceutical Preparations. https://doi.org/10.33899/edusj.2006.78831

MLA

al, Sh.H. Mohamad et. "Spectrophotometric Determination of Promethazine in Pharmaceutical Preparations." 2006. https://doi.org/10.33899/edusj.2006.78831.

Chicago

al, Sh.H. Mohamad et. 2006. "Spectrophotometric Determination of Promethazine in Pharmaceutical Preparations.". https://doi.org/10.33899/edusj.2006.78831.

Harvard

al, S. M. E. 2006, Spectrophotometric Determination of Promethazine in Pharmaceutical Preparations, University of Mosul, College of Education for Pure Science, available at: https://doi.org/10.33899/edusj.2006.78831 [Accessed 8 Aug. 2026].

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Title
Spectrophotometric Determination of Promethazine in Pharmaceutical Preparations
Author / contributors
Sh.H. Mohamad et al
Publisher
University of Mosul, College of Education for Pure Science
Publication year
2006
ISSN
1812-125X
ISSN
1812-125X
Language
English

Subjects

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promethazine; pharmaceutical preparations; spectrophotometric methods
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