News Help Institutional access
Back to results
Bibliographic record · Consultation and access
Artículo

Effect of drug properties on formulation properties of eudragit non effervescent floating microparticulates

Harikumar, S. L. et al · SEDICI UNLP · 2011

Supplementary material available
Quick overview. Review the resource’s basic details, then access the content using the main button. This page shows only the information needed to identify, cite, and open the work.
Author / responsible party
Harikumar, S. L. et al
Publisher
SEDICI UNLP
Year
2011
Language
English

Resource access

Open the content from the main option or choose another available source.

SEDICI UNLP SEDICI UNLP OAI-PMH
Entrar por SEDICI UNLP
Main access

Supplementary material available

El enlace apunta a material asociado, anexos, tablas, datos o página complementaria. No se marca como libro/texto completo.
Open material

Summary

Descripción general del contenido del recurso.

The objective of the present investigation was to investigate the effects of selected drugs (captopril and celecoxib) properties on different parameters drug entrapment, in vitro drug release, release pattern, in vitro drug permeation and buoyancy in the formulation of Eudragit S100 non effervescent floating microparticulates. Microparticulates were in size ranges 268.36-352.27 μm (captopril) and 271.36- 365.54 μm (celecoxib). Encapsulation efficiency of celecoxib was good as compare to captopril. In vitro permeation studies showed in range (ES6) 74.83 μg – (ES1) 79.84 μg (celecoxib), (EU6) 57.01 μg - (EU1) 67.38 μg (captopril). In vitro release followed Non-Fickian diffusion mechanism while in vitro permeation kinetics revealed the super case II transport mechanism. Taken together, water insoluble (celecoxib) drug showed suitable combination with Eudragit S100. This study concluded that the effect of various parameter on the characteristics of Eudragit gastroretentive drug delivery system by non effervescent technique using celecoxib and captopril having different physicochemical characterization. Colegio de Farmacéuticos de la Provincia de Buenos Aires

How to cite

Elegí el formato que necesitás y copiá la referencia al portapapeles.

APA 7

Harikumar, S. L. E. A. (2011). Effect of drug properties on formulation properties of eudragit non effervescent floating microparticulates. http://sedici.unlp.edu.ar/handle/10915/8408

MLA

Harikumar, S. L. et al. "Effect of drug properties on formulation properties of eudragit non effervescent floating microparticulates." 2011. http://sedici.unlp.edu.ar/handle/10915/8408.

Chicago

Harikumar, S. L. et al. 2011. "Effect of drug properties on formulation properties of eudragit non effervescent floating microparticulates.". http://sedici.unlp.edu.ar/handle/10915/8408.

Harvard

Harikumar, S. L. E. A. 2011, Effect of drug properties on formulation properties of eudragit non effervescent floating microparticulates, SEDICI UNLP, available at: http://sedici.unlp.edu.ar/handle/10915/8408 [Accessed 7 Aug. 2026].

Share and print

Save the record, copy its permanent link, or print it as a PDF.

Export reference

You can export the record in common formats for use in a reference manager.

RIS BibTeX

Resource details

Bibliographic information to help confirm that this is the correct material.

Title
Effect of drug properties on formulation properties of eudragit non effervescent floating microparticulates
Author / contributors
Harikumar, S. L. et al
Publisher
SEDICI UNLP
Publication year
2011
Language
English

Subjects

Explore related resources through these subjects.

Farmacia; Partículas; Captopril; Agentes Antiinflamatorios no Esteroides
Copied