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Spectrophotometric Determination of Metoclopramide in Some Pharmaceutical Preparation via Oxidative Coupling Reaction

Nief Ahmad et al · University of Mosul, College of Education for Pure Science · 2006

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Author / responsible party
Nief Ahmad et al
Publisher
University of Mosul, College of Education for Pure Science
Year
2006
ISSN
1812-125X
ISSN
1812-125X
Language
English
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the oxidation of promethazine by sodium hypochlorite and the coupling of the resulting product with metoclopraide in acetic acid medium to form a blue product with maximum absorption at 596 nm. Beer's law is obeyed over the concentration range of (3-30) gml,with molar absorptivity of 1.1104 L.mol-1.A relative standard deviation of the method was less than 1.2% and accuacy was 99.6% The optimum conditions for all colour development are described and the proposed method has been successfully applied for the determination of metoclopramide in pure durg and pharmaceutical formulation.The common excipients and additives did not interfere in this method. <br /> A simple spectrophotometric method for the determination of metoclopramide in a pure form and in dosage forms pharmaceutical preparations has been developed. The proposed method is based on

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APA 7

al, N. A. E. (2006). Spectrophotometric Determination of Metoclopramide in Some Pharmaceutical Preparation via Oxidative Coupling Reaction. https://doi.org/10.33899/edusj.2006.77240

MLA

al, Nief Ahmad et. "Spectrophotometric Determination of Metoclopramide in Some Pharmaceutical Preparation via Oxidative Coupling Reaction." 2006. https://doi.org/10.33899/edusj.2006.77240.

Chicago

al, Nief Ahmad et. 2006. "Spectrophotometric Determination of Metoclopramide in Some Pharmaceutical Preparation via Oxidative Coupling Reaction.". https://doi.org/10.33899/edusj.2006.77240.

Harvard

al, N. A. E. 2006, Spectrophotometric Determination of Metoclopramide in Some Pharmaceutical Preparation via Oxidative Coupling Reaction, University of Mosul, College of Education for Pure Science, available at: https://doi.org/10.33899/edusj.2006.77240 [Accessed 8 Aug. 2026].

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Title
Spectrophotometric Determination of Metoclopramide in Some Pharmaceutical Preparation via Oxidative Coupling Reaction
Author / contributors
Nief Ahmad et al
Publisher
University of Mosul, College of Education for Pure Science
Publication year
2006
ISSN
1812-125X
ISSN
1812-125X
Language
English

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spectrophotometric determination; pharmaceutical preparation; oxidative coupling reaction
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