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Spectrophotometric Assay of Noradrenaline in Pharmaceutical Formulation with Alizarin Red Sulphonate

A. M. S. Al-Delymi et al · University of Mosul, College of Education for Pure Science · 2008

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Author / responsible party
A. M. S. Al-Delymi et al
Publisher
University of Mosul, College of Education for Pure Science
Year
2008
ISSN
1812-125X
ISSN
1812-125X
Language
English
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ABSTRACT<br /> A simple, rapid and sensitive spectrophotometric method for the determination of noradrenaline was developed. The method is based on the proton transfer reaction with alizarin red sulphonate (ARS) in aqueous neutral solution to form violet product showing maximum absorbance at 530 nm with molar absorptivity of 6720 l.mol-1.cm-1. The method follows Beer’s law over the concentration range (0.5-10) g.ml-1. The accuracy (average recovery) of the method is 100.29% and the precision (RSD) of the method is less than 1%.<br /> The method was successfully applied for the determination of noradrenaline in pharmaceutical formulation as injection and the results were in good agreement with the standard addition procedure.

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APA 7

al, A. M. S. A. D. E. (2008). Spectrophotometric Assay of Noradrenaline in Pharmaceutical Formulation with Alizarin Red Sulphonate. https://doi.org/10.33899/edusj.2008.56048

MLA

al, A. M. S. Al-Delymi et. "Spectrophotometric Assay of Noradrenaline in Pharmaceutical Formulation with Alizarin Red Sulphonate." 2008. https://doi.org/10.33899/edusj.2008.56048.

Chicago

al, A. M. S. Al-Delymi et. 2008. "Spectrophotometric Assay of Noradrenaline in Pharmaceutical Formulation with Alizarin Red Sulphonate.". https://doi.org/10.33899/edusj.2008.56048.

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al, A. M. S. A. D. E. 2008, Spectrophotometric Assay of Noradrenaline in Pharmaceutical Formulation with Alizarin Red Sulphonate, University of Mosul, College of Education for Pure Science, available at: https://doi.org/10.33899/edusj.2008.56048 [Accessed 8 Aug. 2026].

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Title
Spectrophotometric Assay of Noradrenaline in Pharmaceutical Formulation with Alizarin Red Sulphonate
Author / contributors
A. M. S. Al-Delymi et al
Publisher
University of Mosul, College of Education for Pure Science
Publication year
2008
ISSN
1812-125X
ISSN
1812-125X
Language
English

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spectrophotometric assay; noradrenaline; pharmaceutical formulation; alizarin red sulphonate
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