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Mulberry extract as an ecofriendly anticoccidial agent: in vitro and in vivo application

Felwa Abdullah Thagfan et al · Colégio Brasileiro de Parasitologia Veterinária · 2020

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Author / responsible party
Felwa Abdullah Thagfan et al
Publisher
Colégio Brasileiro de Parasitologia Veterinária
Year
2020
ISSN
1984-2961
ISSN
1984-2961
Language
English

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Abstract Natural products are ecofriendly agents that can be used against parasitic diseases. Eimeria species cause eimeriosis in many birds and mammals and resistance to available medications used in the treatment of eimeriosis is emerging. We investigated the in vitro and in vivo activity of Morus nigra leaf extracts (MNLE) against sporulation of oocysts and infection of mice with Eimeria papillata. Phytochemical analysis of MNLE showed the presence of seven compounds and the in vitro effects of MNLE, amprolium, DettolTM, formalin, ethanol, and phenol were studied after incubation with oocysts before sporulation. Furthermore, infection of mice with E. papillata induced an oocyst output of approximately 12 × 105 oocysts/g of feces. MNLE significantly decreased oocyst output to approximately 86% and the total number of parasitic stages in the jejunum by approximately 87%. In addition, the reduction in the number of goblet cells in the jejuna of mice was increased after treatment. These findings suggest that mulberry exhibited powerful anticoccidial activity.

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APA 7

al, F. A. T. E. (2020). Mulberry extract as an ecofriendly anticoccidial agent: in vitro and in vivo application. https://doi.org/10.1590/s1984-29612020072

MLA

al, Felwa Abdullah Thagfan et. "Mulberry extract as an ecofriendly anticoccidial agent: in vitro and in vivo application." 2020. https://doi.org/10.1590/s1984-29612020072.

Chicago

al, Felwa Abdullah Thagfan et. 2020. "Mulberry extract as an ecofriendly anticoccidial agent: in vitro and in vivo application.". https://doi.org/10.1590/s1984-29612020072.

Harvard

al, F. A. T. E. 2020, Mulberry extract as an ecofriendly anticoccidial agent: in vitro and in vivo application, Colégio Brasileiro de Parasitologia Veterinária, available at: https://doi.org/10.1590/s1984-29612020072 [Accessed 7 Aug. 2026].

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Title
Mulberry extract as an ecofriendly anticoccidial agent: in vitro and in vivo application
Author / contributors
Felwa Abdullah Thagfan et al
Publisher
Colégio Brasileiro de Parasitologia Veterinária
Publication year
2020
ISSN
1984-2961
ISSN
1984-2961
Language
English

Subjects

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Morus nigra extract; sporulation; eimeriosis; oocysts; mice; jejunum
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