Latent profile analysis and influencing factors of cancer⁃related cognitive impairment in lung cancer patients

ObjectiveTo explore the latent profiles of cognitive function in lung cancer patients and their influencing factors.MethodsA total of 296 lung cancer patients who visited the oncology department of a tertiary grade A hospital in Chongqing from January to August 2025 were selected as the survey subjects.General information questionnaire,Functional Assessment of Cancer Therapy⁃Cognitive Function Scale,Exercise Adherence Scale,and Self⁃Rating Anxiety Scale were used for investigation.Latent profile analysis was employed to explore the latent profiles of cancer⁃related cognitive impairment,while univariate analysis and multinomial Logistic regression analysis were used to investigate the influencing factors of latent profiles in cancer⁃related cognitive impairment patients.ResultsCancer⁃related cognitive impairment patients could be classified into three latent profiles:high cognitive function group(67.2%),moderate cognitive function group(22.6%),and low cognitive function group(10.1%).Multinomial Logistic regression results showed that educational level,tumor stage,age,exercise adherence,and anxiety were influencing factors of latent profiles of cognitive function in lung cancer patients(all <italic>P</italic>&lt;0.05).ConclusionsCancer⁃related cognitive function in lung cancer patients exhibits group heterogeneity.It suggests that healthcare professionals should develop more targeted intervention measures based on the influencing factors of different categories of lung cancer patients' cognitive function levels.