CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

Rodolphe Barrangou; Christophe Fremaux; Hélène Deveau; Melissa Richards; Patrick Boyaval; Sylvain Moineau; Dennis Romero; Philippe Horvath · Science · 2007

Resource page

Quick overview. Review the resource’s basic details, then access the content using the main button. This page shows only the information needed to identify, cite, and open the work.

Author / responsible party

Rodolphe Barrangou; Christophe Fremaux; Hélène Deveau; Melissa Richards; Patrick Boyaval; Sylvain Moineau; Dennis Romero; Philippe Horvath

Publisher

Science

Year

2007

Language

English

Resource access

Open the content from the main option or choose another available source.

OpenAlex OpenAlex Works

Entrar por OpenAlex

Main access

Resource page

Resource reference page. Full text availability has not been automatically confirmed.

Open resource

Summary

Descripción general del contenido del recurso.

Clustered regularly interspaced short palindromic repeats (CRISPR) are a distinctive feature of the genomes of most Bacteria and Archaea and are thought to be involved in resistance to bacteriophages. We found that, after viral challenge, bacteria integrated new spacers derived from phage genomic sequences. Removal or addition of particular spacers modified the phage-resistance phenotype of the cell. Thus, CRISPR, together with associated cas genes, provided resistance against phages, and resistance specificity is determined by spacer-phage sequence similarity.

How to cite

Elegí el formato que necesitás y copiá la referencia al portapapeles.

APA 7

Barrangou, R, Fremaux, C, Deveau, H, Richards, M, Boyaval, P, Moineau, S, Romero, D, & Horvath, P. (2007). CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes. https://doi.org/10.1126/science.1138140

MLA

Barrangou, Rodolphe, et al. "CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes." 2007. https://doi.org/10.1126/science.1138140.

Chicago

Barrangou, Rodolphe, Christophe Fremaux, Hélène Deveau, Melissa Richards, Patrick Boyaval, Sylvain Moineau, Dennis Romero, and Philippe Horvath. 2007. "CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes.". https://doi.org/10.1126/science.1138140.

Harvard

Barrangou, R. et al. 2007, CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes, Science, available at: https://doi.org/10.1126/science.1138140 [Accessed 10 Aug. 2026].

Share and print

Save the record, copy its permanent link, or print it as a PDF.

Export reference

You can export the record in common formats for use in a reference manager.

RIS BibTeX

Resource details

Bibliographic information to help confirm that this is the correct material.

Title: CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

Author / contributors: Rodolphe Barrangou; Christophe Fremaux; Hélène Deveau; Melissa Richards; Patrick Boyaval; Sylvain Moineau; Dennis Romero; Philippe Horvath

Publisher: Science

Publication year: 2007

Language: English

Subjects

Explore related resources through these subjects.

CRISPR; Biology; Palindrome; Genetics; Gene; Genome; Archaea; Bacteria; Bacteriophage; Phenotype; Computational biology; Virology