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THE GREEN FLUORESCENT PROTEIN

Roger Y. Tsien · Annual Review of Biochemistry · 1998

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Author / responsible party
Roger Y. Tsien
Publisher
Annual Review of Biochemistry
Year
1998
Language
English

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In just three years, the green fluorescent protein (GFP) from the jellyfish Aequorea victoria has vaulted from obscurity to become one of the most widely studied and exploited proteins in biochemistry and cell biology. Its amazing ability to generate a highly visible, efficiently emitting internal fluorophore is both intrinsically fascinating and tremendously valuable. High-resolution crystal structures of GFP offer unprecedented opportunities to understand and manipulate the relation between protein structure and spectroscopic function. GFP has become well established as a marker of gene expression and protein targeting in intact cells and organisms. Mutagenesis and engineering of GFP into chimeric proteins are opening new vistas in physiological indicators, biosensors, and photochemical memories.

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APA 7

Tsien, R. Y. (1998). THE GREEN FLUORESCENT PROTEIN. https://doi.org/10.1146/annurev.biochem.67.1.509

MLA

Tsien, Roger Y. "THE GREEN FLUORESCENT PROTEIN." 1998. https://doi.org/10.1146/annurev.biochem.67.1.509.

Chicago

Tsien, Roger Y. 1998. "THE GREEN FLUORESCENT PROTEIN.". https://doi.org/10.1146/annurev.biochem.67.1.509.

Harvard

Tsien, R. Y. 1998, THE GREEN FLUORESCENT PROTEIN, Annual Review of Biochemistry, available at: https://doi.org/10.1146/annurev.biochem.67.1.509 [Accessed 8 Aug. 2026].

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Resource details

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Title
THE GREEN FLUORESCENT PROTEIN
Author / contributors
Roger Y. Tsien
Publisher
Annual Review of Biochemistry
Publication year
1998
Language
English

Subjects

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Aequorea victoria; Green fluorescent protein; Fusion protein; Fluorophore; Protein subcellular localization prediction; Protein engineering; Fluorescence; Mutagenesis; Biology; Cell biology; Biophysics; Chemistry
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