Flavonoids use in glioblastoma multiforme experimental models

Jéssica Paola Alcázar-Arzuza et al · Universidad de Antioquia · 2025

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Author / responsible party

Jéssica Paola Alcázar-Arzuza et al

Publisher

Universidad de Antioquia

Year

2025

ISSN

2145-7166

ISSN

2145-7166

Language

English

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Glioblastoma Multiforme (GBM) represents tumors that develop in the Central Nervous System (CNS) with the highest malignancy, incidence and prevalence. Flavonoid therapy has been gaining strength as an alternative adjuvant that counteracts the appearance and development of various cancers, including GBM. The objective of this review is to analyze the use of flavonoids in GBM therapy in a ten-year window (2013-2023). Fifty-one articles were reviewed, including original articles and bibliographic reviews. Flavonoids have been tested in different GBM in vitro models, decreasing proliferation and angiogenesis, activating signaling pathways and redirecting cell activity to alternative pathways that promote apoptosis and cell repair.

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APA 7

al, J. P. A. A. E. (2025). Flavonoids use in glioblastoma multiforme experimental models. https://doi.org/10.17533/udea.acbi/v47n123a09

MLA

al, Jéssica Paola Alcázar-Arzuza et. "Flavonoids use in glioblastoma multiforme experimental models." 2025. https://doi.org/10.17533/udea.acbi/v47n123a09.

Chicago

al, Jéssica Paola Alcázar-Arzuza et. 2025. "Flavonoids use in glioblastoma multiforme experimental models.". https://doi.org/10.17533/udea.acbi/v47n123a09.

Harvard

al, J. P. A. A. E. 2025, Flavonoids use in glioblastoma multiforme experimental models, Universidad de Antioquia, available at: https://doi.org/10.17533/udea.acbi/v47n123a09 [Accessed 8 Aug. 2026].

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Title: Flavonoids use in glioblastoma multiforme experimental models

Author / contributors: Jéssica Paola Alcázar-Arzuza et al

Publisher: Universidad de Antioquia

Publication year: 2025

ISSN: 2145-7166

ISSN: 2145-7166

Language: English

Subjects

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cell culture; cellular therapy; flavonoids; glioblastoma multiforme; in vitro models; phytotherapy