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Study of antitumor activity in breast cell lines using silver nanoparticles produced by yeast

Ortega, Francisco Gabriel et al · Dove Press · 2015

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Author / responsible party
Ortega, Francisco Gabriel et al
Publisher
Dove Press
Year
2015
ISSN
2021-2031
ISSN
2021-2031
Language
English

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In the present article, we describe a study of antitumor activity in breast cell lines using silver nanoparticles (Ag NPs) synthesized by a microbiological method. These Ag NPs were tested for their antitumor activity against MCF7 and T47D cancer cells and MCF10-A normal breast cell line. We analyzed cell viability, apoptosis induction and endocytosis activity of those cell lines and we observed that the effects of the biosynthesized Ag NPs were directly related with the endocytosis activity. Moreover, Ag NPs had higher inhibition efficacy in tumor lines than in normal lines of breast, which is due to the higher endocytic activity of tumor cells comparing to normal cells. In this way, we are demonstrating that biosynthesized Ag NPs can be an alternative for the treatment of tumors. Fil: Ortega, Francisco Gabriel. Universidad de Granada. Centro de Genómica e Investigación Oncológica; España Fil: Fernández Baldo, Martín Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico San Luis. Instituto de Química de San Luis; Argentina

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APA 7

Ortega, F. G. E. A. (2015). Study of antitumor activity in breast cell lines using silver nanoparticles produced by yeast. http://hdl.handle.net/11336/5780

MLA

Ortega, Francisco Gabriel et al. "Study of antitumor activity in breast cell lines using silver nanoparticles produced by yeast." 2015. http://hdl.handle.net/11336/5780.

Chicago

Ortega, Francisco Gabriel et al. 2015. "Study of antitumor activity in breast cell lines using silver nanoparticles produced by yeast.". http://hdl.handle.net/11336/5780.

Harvard

Ortega, F. G. E. A. 2015, Study of antitumor activity in breast cell lines using silver nanoparticles produced by yeast, Dove Press, available at: http://hdl.handle.net/11336/5780 [Accessed 8 Aug. 2026].

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Title
Study of antitumor activity in breast cell lines using silver nanoparticles produced by yeast
Author / contributors
Ortega, Francisco Gabriel et al
Publisher
Dove Press
Publication year
2015
ISSN
2021-2031
ISSN
2021-2031
Language
English

Subjects

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APOPTOSIS; BREAST CANCER; SILVER NANOPARTICLES; NANOTECHNOLOGY; CANCER; MICROBIOLOGICAL SYNTHESIS; https://purl.org/becyt/ford/2.10; https://purl.org/becyt/ford/2
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