Compact pulsed thulium-doped fiber laser for topographical patterning of hydrogels

We report the generation of high energy 2 μm picosecond pulses from a thulium-doped fiber master oscillator power amplifier system. The all-fiber configuration was realized by a flexible large-mode area photonic crystal fiber (LMA-PCF). The amplifier output is a linearly-polarized 1.5 ns, 100 kHz pulse train with a pulse energy of up to 250 μJ. Pulse compression was achieved with (2+2)-pass chirped volume Bragg grating (CVBG) to obtain a 2.8 ps pulse width with a total pulse energy of 46 μJ. The overall system compactness was enabled by the all-fiber amplifier design and the multi-pass CVBG-based compressor. The laser output was then used to demonstrate high-speed direct-writing capability on a temperature-sensitive biomaterial to change its topography (i.e. fabricate microchannels, foams and pores). The topographical modifications of biomaterials are known to influence cell behavior and fate which is potentially useful in many cell and tissue engineering applications.