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Confocal laser speckle autocorrelation imaging of dynamic flow in microvasculature

E Du et al · Editorial Office of Opto-Electronic Journals Group, Institute of Optics and Electronics, CAS, China · 2022

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Author / responsible party
E Du et al
Publisher
Editorial Office of Opto-Electronic Journals Group, Institute of Optics and Electronics, CAS, China
Year
2022
ISSN
2096-4579
ISSN
2096-4579
Language
English

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Laser speckle imaging has been widely used for in-vivo visualization of blood perfusion in biological tissues. However, existing laser speckle imaging techniques suffer from limited quantification accuracy and spatial resolution. Here we report a novel design and implementation of a powerful laser speckle imaging platform to solve the two critical limitations. The core technique of our platform is a combination of line scan confocal microscopy with laser speckle autocorrelation imaging, which is termed Line Scan Laser Speckle Autocorrelation Imaging (LS-LSAI). The technical advantages of LS-LSAI include high spatial resolution (~4.4 μm) for visualizing and quantifying blood flow in microvessels, as well as video-rate imaging speed for tracing dynamic flow.

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APA 7

al, E. D. E. (2022). Confocal laser speckle autocorrelation imaging of dynamic flow in microvasculature. https://doi.org/10.29026/oea.2022.210045

MLA

al, E Du et. "Confocal laser speckle autocorrelation imaging of dynamic flow in microvasculature." 2022. https://doi.org/10.29026/oea.2022.210045.

Chicago

al, E Du et. 2022. "Confocal laser speckle autocorrelation imaging of dynamic flow in microvasculature.". https://doi.org/10.29026/oea.2022.210045.

Harvard

al, E. D. E. 2022, Confocal laser speckle autocorrelation imaging of dynamic flow in microvasculature, Editorial Office of Opto-Electronic Journals Group, Institute of Optics and Electronics, CAS, China, available at: https://doi.org/10.29026/oea.2022.210045 [Accessed 8 Aug. 2026].

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Title
Confocal laser speckle autocorrelation imaging of dynamic flow in microvasculature
Author / contributors
E Du et al
Publisher
Editorial Office of Opto-Electronic Journals Group, Institute of Optics and Electronics, CAS, China
Publication year
2022
ISSN
2096-4579
ISSN
2096-4579
Language
English

Subjects

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laser speckle; autocorrelation; confocal; line scan; flow
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